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FYS-KJM9740 - MR-theory and medical diagnostics

Facts about this course:
Credits:10
Level:Ph.D. level course
Teaching semester:Every spring semester

If the course is offered, a minimum of four students is required for ordinary lectures to take place. If less than four students participate, an exam will be given, but one should not expect ordinary teaching.

Examination semester:Every spring semester
Language of instruction:English if requested by exchange students, otherwise Norwegian
Administrated by:Department of Physics
Detailed course information - Current and previous semesters:

Course content

A detailed introduction to the concepts of chemical shift, coupling constant, relaxation times and diffusion. Analysis of AB-spectra, based on quantum mechanical principles. Relaxation times are important in both nuclear magnetic resonance spectroscopy (MRS) and magnetic tomography (MRI) and are discussed with use of the Bloch equations. The principles of MRI and the construction of the MR tomograph, design and optimalisation of pulse sequences, identification of picture artefacts and examples on how to use MRS/MRI. It will also contain an introduction in MR-related pictureanalysis with focus on functional(dynamic) analysis of MR-data.

Learning outcomes

After finishing the course the student should be able to:

  • understand the basic concept of how nuclear magnetisation is created or formed.
  • understand the effect of radio frequency-pulses on these magnetisations.
  • formulate the Bloch equation (how magnetisations are affected by relaxation and diffusion) and solve this equation under various conditions.
  • understand the basic principles of NMR spectroscopy (chemical shift, J-coupling, 1-order and 2-order spectra).
  • understand the basic concept of MR image acquisition and reconstruction:
    - spatial localisation of MR signal in 2D and 3D
    - k-space formulation
    - pulse sequence design
    - signal acquisition acceleration techniques
  • understand the contrast mechanisms in MRI based on:
    - relaxation properties of tissues
    - flow and physiology properties of tissues (flow, diffusion etc.)
  • understand the link between MR sequence parameters and image contrast.
  • apply the above theory to simple examples.

Admission

To participate in this course you must have an admission to a Ph.D.-programme at a Norwegian University or University College.

If you do not have an admission to the Ph.D.-Programme in Science at The Faculty of Mathematics and Natural Sciences at UiO, you have to apply for hospitantstatus (norwegian text) . For more information, please contact the Department.

Prerequisites

Recommended prior knowledge

MAT1110 - Calculus and linear algebraFYS2140 - Quantum physics and/or KJM1060 - Struktur og spektroskopi.

Overlap

10 credits overlap against KJ-FY397.

10 credits with FYS-KJM4740 - MR-theory and medical diagnostics

Teaching

The course extends over a full semester with 40 hours of lectures and 30 hours of practical work. There will also be laboratory assignments and students will have to read and lecture about a scientific article related to the curriculum.

Exam information

Evaluation of project work and a final oral exam.

Assessment and grading

Students are awarded either a passing or a failing grade. Read more about the grading system .

Contact us

Department of Physics

Visiting address: 
Physics building, Sem Sælandsvei 24

Visiting hours: 
Monday-friday 08:00-15:45

Postal address: 
P.O. Box. 1048, Blindern
NO-0316 OSLO

Phone: +47 22 85 64 23
Fax: +47 22 85 64 22
E-mail: 
Web: http://www.mn.uio.no/fysikk/english/