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FYS9720 - Cellular radio biology

Course content

Mechanisms for radiation absorption on a molecular and cellular level. Effects on the DNA. Cancer and genetic injuries. Models for cell inactivation and dose rate dependence. Variations of cell cycles due to sensibility to radiation. Radiation modifying factors. The relation between radiation injuries and the regulation of cell growth and cell death (apoptosis). Effects of adaptive radiation. Radiation therapy and dose/time relations, mathematical modelling of dose fractionation, calculation of iso-effect relations. Brachytherapy (continuos and pulsed dose-rate). Radiation carcinogenesis, radiation-induced genetical defects and radiation hormesis.

Learning outcome

To provide the student with a general background for the influence of ionising radiation on cells and cellular molecules and an introduction to the methods of radiation therapy.

Admission

PhD candidates from the University of Oslo should apply for classes and register for examinations through Studentweb.

If a course has limited intake capacity, priority will be given to PhD candidates who follow an individual education plan where this particular course is included. Some national researchers’ schools may have specific rules for ranking applicants for courses with limited intake capacity.

PhD candidates who have been admitted to another higher education institution must apply for a position as a visiting student within a given deadline.

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Prerequisites

Formal prerequisite knowledge

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Recommended previous knowledge

FYS3710 - Biophysics and medical physics

Overlapping courses

10 credits overlap against FYS396.

10 credits with FYS4720 - Cellular radio biology

Teaching

The course extends over a full semester with 2-4 hours of teaching per week (lectures and colloquia). Compulsory lab work. The course also includes extra introduction to a selected theme for ph.d.-candidates.

Access to teaching

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Examination

Final oral exam.

Examination support material

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Language of examination

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Grading scale

Grades are awarded on a pass/fail scale. Read more about the grading system.

Explanations and appeals

You may request an explanation of your grades, and you may also appeal against your grades or make a complaint about formal examination errors. Read more about explanations and appeals.

Resit an examination

You can usually resit an exam, but the conditions depend on whether you had a valid reason for absence from the regular exam. Read more about resitting an exam.

Withdrawal from an examination

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Special examination arrangements

If you have a disability or a health problem that entails significant inconvenience in an examination situation, you may be considered for special examination arrangements. Mothers who are breastfeeding may apply for extra time to complete the exam.

Evaluation

Feedback from our students is essential to us in our efforts to ensure and further improve the high quality of our programmes and courses. All courses are subject to continuous evaluation. At regular intervals we also ask students on a particular course to participate in a more comprehensive, periodic evaluation of this course.

Facts about this course

Credits

10

Level

PhD

Teaching

Every autumn

If the course is offered, a minimum of four students is required for ordinary lectures to take place. If less than four students participate, an exam will be given, but one should not expect ordinary teaching.

Examination

Every autumn

Teaching language

Norwegian

Semester pages

Teaching schedule, syllabus, examination date