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MBV3070 - Bioinformatics

Course content

Biological sequence databases. Parwise and multiple sequence alignments, analysis of genomic DNA sequences, protein modeling, DNA arrays. Introduction to perl programming.

Learning outcomes

An understanding of how a comparison of biological sequences can give information on the function and evolution of the sequences. How algorithms for optimal pairwise sequence alignments and for database searches work. A knowledge of tools for homology-based modeling of three-dimensional protein structures. DNA microarrays: Principle and analysis of the results. Knowledge about the use of perl to construct and modify computer programs for bioinformatical analyses.

Admission

Students at UiO must apply for courses in StudentWeb.

International applicants, if you are not already enrolled as a student at UiO, please see our information about admission requirements and procedures for international applicants.

Prerequisites

Formal prerequisites

MBV1030 - General biochemistry or corresponding. MBV2010 - Molecular biology or corresponding (from 2008).

In addition to fulfilling the Higher Education Entrance Qualification, applicants have to meet the following special admission requirements:

One of these:

• Mathematics R1
• Mathematics (S1+S2)

And and in addition one of these:

• Mathematics (R1+R2)
• Physics (1+2)
• Chemistry (1+2)
• Biology (1+2)
• Information technology (1+2)
• Geosciences (1+2)
• Technology and theories of research (1+2)

The special admission requirements may also be covered by equivalent studies from Norwegian upper secondary school or by other equivalent studies. Read more about special admission requirements.

Recommended prior knowledge

MAT1000 - Mathematics for applications I. MBV2010 - Molecular biology (prerequisite from 2008).

Teaching

Lectures (24 hours), work in PC-lab (48 hours). Work in PC-lab is compulsory. The compulsory work has to be approved before the exam. Some selected PC-reports will be a part of the exam.

Exam information

Some selected PC-work reports (counts ca 25%). Written exam, 3 hours, in June (counts ca 75%). Allowed examination aids: None. Letter grading.

This subject offer new examination in the beginning of the subsequent term for candidates who withdraw during an ordinary examination or fail an ordinary examination. More information about new examination can be found on the faculty's site.

Evaluation of this course

Feedback from our students is essential to us in our efforts to ensure and further improve the high quality of our programmes and courses. As a student at the University of Oslo you will therefore be asked to participate in various types of evaluation of our courses, facilities and services. All courses are subject to continuous evaluation. At regular intervals we also ask students on a particular course to participate in a more comprehensive, in-depth evaluation of this course, a so called "periodic evaluation".

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