MBV9270 - BIOSTRUCT - Advanced Glycobiology
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Course content
The course has been initiated to give a comprehensive overview of aspects of glycobiology which is an important research area at The Faculty of Mathematics and Natural Sciences. Proteins and lipids are modified with glycans through post-translational modifications and become glycoproteins, proteoglycans, and glycolipids which can participate in specific molecular interactions or transport mechanisms of biological importance. At the same time, glycans at the cell surface are often attack sites for harmful microorganisms, while complex glycans of plant origin stimulate the immune system.
Learning outcomes
The course introduces the students to synthesis mechanisms for glycoproteins and glycolipids in different organisms, both prokaryotic and eukaryotic. Examples are presented to how glycans influence molecular structure and biological interactions with other proteins and macromolecules in general. In addition, the role of glycans in intracellular transport and other cellular mechanisms is described. Glycans at the cell surface often play a decisive role when microorganisms like virus and bacteria enter the epithelium of different tissues, and in this way causes disease. Examples of analytical techniques are also presented; X-ray crystallography, mass spectrometry, and other chromatographic methods
Admission
To participate in this course you must have an admission to a Ph.D.-programme at a Norvegian University or University College.
If you do not have an admission to the Ph.D.-Programme in Science at The Faculty of Mathematics and Natural Sciences at UiO, you have to apply as a visiting phd student
For more information, please contact the Department.
The examination in this course is not available for external candidates. Only students admitted to the course may sit for the examination.
Prerequisites
Recommended prior knowledge
MBV1030 - General biochemistry and MBV3010 - Advanced cell biology or corresponding knowledge.
Teaching
The course is given as 30 hours lectures and 10 hours colloquia/group work with oral presentations. All teaching sessions are obligatory and constitute the curriculum together with hand-outs.
Information about room and teaching hours is on the semester pages for the course MBV4270 - BIOSTRUCT - Advanced Glycobiology
The course is taught intensivelly full time for two weeks in late spring term.
Exam information
Presented group work must be approved and is a prerequisite to pass the final exam.
An essay over a given subject which must be approved before the exam.
A final written exam (3 hours) is held one week after the end of the course.
General information about exam
Exam resources
No special exam resources are allowed.
Assessment and grading
Students are awarded either a passing or a failing grade. Read more about the grading system .
Explanations and appeals
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Students can request an explanation of their grades, and can also appeal against their grades or make a complaint about formal examination errors. Read more about explanations and appeals
Possibility of make-up exams and re-takes
Dette emnet tilbyr ny eksamen for studenter som stryker eller trekker seg under ordinær eksamen. Tidspunkt avtales nærmere.
You can usually resit an exam, but the conditions depend on whether you had a valid reason for absence from the regular exam. Read more about resitting an exam .
Withdrawing from exams and limits on re-takes
A student can sit for this exam up to 3 times. If a student wishes to withdraw from the exam, s/he must do this in StudentWeb at least two weeks prior to the first day of the exam. Failure to do so will be counted as one of the three opportunities to sit for the exam.
Exam options for students with special needs
Students may apply for access to alternative exam resources or exam forms on the basis of chronic illness and/or special needs that create a marked disadvantage to other students in the exam situation. Mothers who are breastfeeding may apply for extra time to complete the exam.
Evaluation of this course
Feedback from our students is essential to us in our efforts to ensure and further improve the high quality of our programmes and courses. As a student at the University of Oslo you will therefore be asked to participate in various types of evaluation of our courses, facilities and services. All courses are subject to continuous evaluation. At regular intervals we also ask students on a particular course to participate in a more comprehensive, in-depth evaluation of this course, a so called "periodic evaluation".
Other information
The course is created by GYCONOR at The Faculty of Mathematics and Natural Sciences with partners from Pharmaceutical Dept., Chemistry Dept. and Dept. of Molecular Biosciences. The course is recommended for master and PhD students in this research field, but others are very welcome.
Contact us
Department of Molecular Biosciences
Visiting address:
Kristine Bonnevies hus, Blindernveien 31
Visiting hours:
Tirsdag-torsdag 12:15-15:00
Postal address:
P.O.Box1041, Blindern
0316 Oslo
Fax: +47 22 85 60 41
E-mail: studieinfo@imbv.uio.no
Web: http://www.mn.uio.no/imbv/english/