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  • MBV9300BTS

MBV9300BTS - BIOSTRUCT- Membrane Proteins; from Isolation to Crystals

Course content

The course will be highly focussed on methodology and decision process involved in membrane protein crystallisation. The student will be grouped into 3-4 group that will rotate between different stations, within the laboratory. First station will involve “Membrane proteins identification and small scale membrane isolation” the second station “Large scale membrane protein purification” and the third station “Membrane Protein lipidation and Crystallization trials”. There will be 3 overview talks from both international and internal speakers.

Learning outcomes

You will have "hands-on" experience with membrane protein expression, solubility studies which involves handling of detergents as well as purification of membrane proteins and crystallization.

Admission

To participate in this course you must have an admission to a PhD-programme at a Norwegian University or University College.

If you do not have an admission to the PhD-programme in Science at The Faculty of Mathematics and Natural Sciences at UiO, you have to apply as a visiting PhD student

For more information, please contact the Department. The deadline for application follows the official deadlines.
With free capacity the course is also open for PhD-students from other countries.
Please contact PhD Preben Morth for more information about the course or Torill Rørtveit questions about admission.

Only students admitted to the course may take part in instruction and tuition and sit for the examination.

The examination in this course is not available for external candidates. Only students admitted to the course may sit for the examination.

Prerequisites

Recommended prior knowledge

Basic knowledge of protein structure and protein structure determination.

Overlap

No overlap with other courses.

Teaching

Practical lab. work and teoretical lessons in full time for one week. The teaching will be at Centre for Molecular Medicine (NCMM) Forskningsparken, Blindern, Oslo
A selected set of articles should be studied before course start. Estimated time for this activity: one week.

Exam information

Written group report (expected 1 week after the course)

Assessment and grading

Students are awarded either a passing or a failing grade. Read more about the grading system .

Explanations and appeals

Students can request an explanation of their grades, and can also appeal against their grades or make a complaint about formal examination errors. Read more about explanations and appeals

Possibility of make-up exams and re-takes

You can usually resit an exam, but the conditions depend on whether you had a valid reason for absence from the regular exam. Read more about resitting an exam .

Exam options for students with special needs

Students may apply for access to alternative exam resources or exam forms on the basis of chronic illness and/or special needs that create a marked disadvantage to other students in the exam situation. Mothers who are breastfeeding may apply for extra time to complete the exam.

Other information

The course is part of the BioStruct PhD-school (National Graduate School in Structural Biology).
BioStruct partly covers the costs for travel and accommodation for BioStruct students partici¬pating in national courses at Norwegian universities other than the student’s home-institution. For information contact Vibeke Os, biostruct@uit.no / 776 44647

If the number of applicants exceeds the capacity of the course, 75% of the course admissions will be reserved students attending the PhD school, BioStruct.

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