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MF9390 - Epigenetics, development and disease.

Course content

This is a 40 hour course consisting of formal lectures on epigenetics and stem cells, guest lectures on specific issues relating to epigenetics, lunch research seminars by the guest lecturers, group work and practical courses. The Objective of the course is to introduce the concept of epigenetics as a key mechanism of regulation of gene expression steering development and cell fate, and which can be affected in disease. The course will require a significant amount of personal work in addition.

Learning outcome

1. A thorough understanding of epigenetics and its importance in gene regulation and disease
2. Acquisition of global theoretical and practical concepts around analysis of DNA methylation and histone modifications
3. A practical hands-on experience in performing a chromatin immunoprecipitation assay - one of the mostly used assays in any laboratory working on gene regulation.
4. Training in synthesizing and presenting a research article in the field of epigenetics

Admission

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Ph.D. candidates at the University of Oslo and students at the Medical Student Research Programme will get first priority to the course. External applicants will be admitted if there are any available places.


Maximum number of participants is 20.

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Prerequisites

Formal prerequisite knowledge

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Cell biology, molecular biology

Recommended previous knowledge

Basic mechanisms of regulation of gene expression

Teaching

The course will not be held autumn 2012.

This is a 40 hour course consisting of formal lectures (~8 h), 3 guest lectures (2 h each), 3 lunch research seminars, group work (journal club and practical work), and a practical course on chromatin immunoprecipitation.

NB! You have to participate in at least 80 % of the teaching to be able to pass the course. Attendance at lectures will be registered.

Access to teaching

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Examination

Examination will be a pass/fail. There will be no formal examination. Rather, evaluation will include registered obligatory participation in all lectures, seminars, group work and lab work, quality of journal club presentation, success in solving the practical problem paused, and knowledge shown on the course topic through questions asked throughout the course, in particular during the practical work.

Examination support material

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Language of examination

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Grading scale

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Explanations and appeals

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Students can request an explanation of their grades, and can also appeal against their grades or make a complaint about formal examination errors. Read more about explanations and appeals

Resit an examination

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Withdrawal from an examination

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Special examination arrangements

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Evaluation

Feedback from our students is essential to us in our efforts to ensure and further improve the high quality of our programmes and courses. All courses are subject to continuous evaluation. At regular intervals we also ask students on a particular course to participate in a more comprehensive, periodic evaluation of this course.

Facts about this course

Credits

5

Level

PhD

Teaching

Every autumn

Examination

Every autumn

Teaching language

English

Semester pages

Teaching schedule, syllabus, examination date