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MF9390 - Epigenetics, development and disease.

Facts about this course:
Credits:5
Level:Ph.D. level course
Teaching semester:Every autumn semester
Examination semester:Every autumn semester
Language of instruction:English
Administrated by:Institute of Basic Medical Sciences, Department of Biochemistry
Detailed course information - Current and previous semesters:

Course content

This is a 40 hour course consisting of formal lectures on epigenetics and stem cells, guest lectures on specific issues relating to epigenetics, lunch research seminars by the guest lecturers, group work and practical courses. The Objective of the course is to introduce the concept of epigenetics as a key mechanism of regulation of gene expression steering development and cell fate, and which can be affected in disease. The course will require a significant amount of personal work in addition.

Learning outcomes

1. A thorough understanding of epigenetics and its importance in gene regulation and disease
2. Acquisition of global theoretical and practical concepts around analysis of DNA methylation and histone modifications
3. A practical hands-on experience in performing a chromatin immunoprecipitation assay - one of the mostly used assays in any laboratory working on gene regulation.
4. Training in synthesizing and presenting a research article in the field of epigenetics

Admission

Ph.D. candidates at the University of Oslo and students at the Medical Student Research Programme will get first priority to the course. External applicants will be admitted if there are any available places.

The StudentWeb is open for registration from 1st June to 1st August.

Registration form for external appalicants - Final date for registration 1st August.

Maximum number of participants is 20.

Prerequisites

Formal prerequisites

Cell biology, molecular biology

Recommended prior knowledge

Basic mechanisms of regulation of gene expression

Teaching

The course will be taught on the following dates:

12 - 16th September 2011

This is a 40 hour course consisting of formal lectures (~8 h), 3 guest lectures (2 h each), 3 lunch research seminars, group work (journal club and practical work), and a practical course on chromatin immunoprecipitation.

NB! You have to participate in at least 80 % of the teaching to be able to pass the course. Attendance at lectures will be registered.

Exam information

Examination will be a pass/fail. There will be no formal examination. Rather, evaluation will include registered obligatory participation in all lectures, seminars, group work and lab work, quality of journal club presentation, success in solving the practical problem paused, and knowledge shown on the course topic through questions asked throughout the course, in particular during the practical work.

Explanations and appeals

Students can request an explanation of their grades, and can also appeal against their grades or make a complaint about formal examination errors. Read more about explanations and appeals

Evaluation of this course

Feedback from our students is essential to us in our efforts to ensure and further improve the high quality of our programmes and courses. As a student at the University of Oslo you will therefore be asked to participate in various types of evaluation of our courses, facilities and services. All courses are subject to continuous evaluation. At regular intervals we also ask students on a particular course to participate in a more comprehensive, in-depth evaluation of this course, a so called "periodic evaluation".

Contact us

The Faculty of Medicine, Section for research education

Visiting address: 
Sogn Arena, 2. etasje. Klaus Torgårdsvei 3, 0372 Oslo

Visiting hours: 
Monday - Friday 09.00 - 15.00

Postal address: 
P.O. Box 1078 Blindern
0316 Oslo

Phone: 22 84 53 00
Fax: 22 84 53 01
E-mail: 
Web: http://www.uio.no/forskning/doktorgrad-karriere/forskerutdanning/