Knut Tomas Dalen

Bilde av Knut Tomas Dalen
English version of this page
Telefon +47 22851515
Mobiltelefon +47 91134097
Rom 2201
Brukernavn
Besøksadresse Sognsvannsveien 9 Domus Medica 0372 Oslo
Postadresse Postboks 1046 Blindern 0317 Oslo

Faglige interesser

  • Molekylær ernæring
  • Lipidmetabolisme
  • Lipiddråper
  • Transkripsjonell regulering
  • Livsstilssykdommer som metabolsk syndrom,  type 2 diabetes og hjerte- og karsykdom

Undervisning

Bakgrunn

Utdannelse:

  • June 2005: Dr. Philos, (veileder Prof. Hilde Nebb), Avdeling for ernæringsvitenskap, Universitet i Oslo.
  • 1997-1999: Candidatus Scientiarum - biokjemi, Institutt for Biovitenskap og Avdeling for ernæringsvitenskap, Universitet i Oslo.
  • 1995-1996: Kjemi/Biokjemi – diverse kurs. Universitet i Oslo..
  • 1992-1995: Kjemiingeniør – med spesialisering i Bioteknologi, Høgskolen i Østfold, Sarpsborg.

Arbeidserfaring:

  • 2009-2013: Post doktor (UiO, Refsum/Nebb), Avdeling for ernæringsvitenskap, Universitet i Oslo.
  • 01-09.2009: Post doktor (Chaudhry-gruppen), Bioteknologisenteret, Universitet i Oslo.
  • 2007-2008: Forsker (UiO, Nebb), Avdeling for ernæringsvitenskap, Universitet i Oslo.
  • 2005-2007: Gjesteforsker (Londos), Membrane Regulation Section, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), US.
  • 2000-2005: Stipendiat (UiO, Nebb), Avdeling for ernæringsvitenskap, Universitet i Oslo.
  • 01-06.2000: Gjesteforsker. (Auwerx). ”Institut de Génétique et de Biologie Molélulaire et Cellulaire (IGBMC)”, INSERM, Illkirch, France.
  • 1999-2000: Laboratorieassistent ( Nebb), Avdeling for ernæringsvitenskap, Universitet i Oslo.

Priser

  • 2005: Intramural Visiting Fellow Award: NIDDK, NIH, Bethesda, US.
  • 2005: Research Travel Award: Henning och Johan Throne-Holst Foundation
  • 2007: Research Travel Award: Henning och Johan Throne-Holst Foundation

Samarbeid

  • Prof. Alan Kimmel, NIDDK, National Institutes of Health, (NIH), US.
  • Prof. Hilde Nebb, Avdeling for ernæringsvitenskap, Universitetet I Oslo.
  • Prof. Helga Refsum, Avdeling for ernæringsvitenskap, Universitetet I Oslo.
  • Prof. Christian Drevon og Dr. Torgeir Holen, Avdeling for ernæringsvitenskap, Universitetet I Oslo.
  • Prof. Jan Boren, og Prof. Malin Levin, Sahlgranska Center for Cardiovascular and Metabolic Research (CMR), Gøteborg, Sverige.
  • Profs. Arild Rustan og Hege Thoresen, Farmasøytisk institutt, Universitetet i Oslo.
Emneord: Ernæring, Diabetes og hormoner, Muskel og skjelett, Lipider, Lipiddråper, Transkripsjon, Kjernereseptorer

Publikasjoner

  • Doncheva, Atanaska Ivanova; Li, Yuchuan; Khanal, Prabhat; Hjorth, Marit; Kolset, Svein Olav & Norheim, Frode Amador [Vis alle 8 forfattere av denne artikkelen] (2023). Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice. Journal of Lipid Research. ISSN 0022-2275. 64(12). doi: 10.1016/j.jlr.2023.100461. Fulltekst i vitenarkiv
  • Li, Yuchuan; Amrutkar, Manoj; Finstadsveen, Anette V.; Dalen, Knut Tomas; Verbeke, Caroline Sophie & Gladhaug, Ivar Prydz (2023). Fatty acids abrogate the growth-suppressive effects induced by inhibition of cholesterol flux in pancreatic cancer cells. Cancer Cell International. ISSN 1475-2867. 23. doi: 10.1186/s12935-023-03138-8. Fulltekst i vitenarkiv
  • Pourteymour, Shirin; Drevon, Christian André; Dalen, Knut Tomas & Norheim, Frode Amador (2023). Mechanisms Behind NAFLD: a System Genetics Perspective. Current Atherosclerosis Reports. ISSN 1523-3804. 25(11), s. 869–878. doi: 10.1007/s11883-023-01158-3.
  • Hindar, Kjetil; Bodin, Johanna Eva; Duale, Nur; Jevnaker, Anne-Marthe Ganes; Garseth, Åse Helen & Malmstrøm, Martin [Vis alle 15 forfattere av denne artikkelen] (2023). Environmental risk assessment of genetically modified sterile VIRGIN® Atlantic salmon for use in research trials in aquaculture sea-cages. VKM Report. ISSN 2535-4019. 2023:20, s. 1–94. Fulltekst i vitenarkiv
  • Li, Yanjiao; Wang, Yunhao; Vera-Rodriguez, Maria; Lindeman, Leif Christopher; Skuggen, Linda Ellevog & Rasmussen, Erik Magne Koscielniak [Vis alle 21 forfattere av denne artikkelen] (2023). Single-cell m6A mapping in vivo using picoMeRIP–seq. Nature Biotechnology. ISSN 1087-0156. doi: 10.1038/s41587-023-01831-7. Fulltekst i vitenarkiv
  • Wang, Yunhao; Li, Yanjiao; Skuland, Trine; Zhou, Chengjie; Li, Aifu & Hashim, Adnan [Vis alle 13 forfattere av denne artikkelen] (2023). The RNA m<sup>6</sup>A landscape of mouse oocytes and preimplantation embryos. Nature Structural & Molecular Biology. ISSN 1545-9993. 30(5), s. 703–709. doi: 10.1038/s41594-023-00969-x.
  • Meen, Astri Jeanette; Doncheva, Atanaska Ivanova; Böttcher, Yvonne; Dankel, Simon N; Hoffmann, Anne & Blüher, Matthias [Vis alle 16 forfattere av denne artikkelen] (2023). Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue. International Journal of Molecular Sciences. ISSN 1661-6596. 24(8). doi: 10.3390/ijms24086884. Fulltekst i vitenarkiv
  • Canet, Francisco; Christensen, Jacob J.; Victor, Victor M.; Hustad, Kristin Solheim; Ottestad, Inger & Rundblad, Amanda [Vis alle 11 forfattere av denne artikkelen] (2022). Glycated proteins, glycine, acetate, and monounsaturated fatty acids may act as new biomarkers to predict the progression of type 2 diabetes: Secondary analyses of a randomized controlled trial. Nutrients. ISSN 2072-6643. 14(23), s. 1–19. doi: 10.3390/nu14235165. Fulltekst i vitenarkiv
  • Hjorth, Marit; Doncheva, Atanaska Ivanova; Norheim, Frode Amador; Ulven, Stine Marie; Holven, Kirsten Bjørklund & Sæther, Thomas [Vis alle 7 forfattere av denne artikkelen] (2022). Consumption of salmon fishmeal increases hepatic cholesterol content in obese C57BL/6 J mice. European Journal of Nutrition. ISSN 1436-6207. 61, s. 4027–4043. doi: 10.1007/s00394-022-02930-y. Fulltekst i vitenarkiv
  • Doncheva, Atanaska Ivanova; Romero, Silvana Angelica Troncoso; Ramirez-Garrastacho, Manuel; Lee-Ødegård, Sindre; Kolnes, Kristoffer Jensen & Tangen, Daniel S. [Vis alle 11 forfattere av denne artikkelen] (2022). Extracellular vesicles and microRNAs are altered in response to exercise, insulin sensitivity and overweight. Acta Physiologica. ISSN 1748-1708. 236(4). doi: 10.1111/apha.13862. Fulltekst i vitenarkiv
  • Torp, May-Kristin; Ranheim, Trine; Schjalm, Camilla; Hjorth, Marit; Heiestad, Christina Mathisen & Dalen, Knut Tomas [Vis alle 13 forfattere av denne artikkelen] (2022). Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasis. Frontiers in Immunology. ISSN 1664-3224. 13. doi: 10.3389/fimmu.2022.870811. Fulltekst i vitenarkiv
  • Hjorth, Marit; Galigniana, Natalia; Ween, Ola; Ulven, Stine Marie; Holven, Kirsten Bjørklund & Dalen, Knut Tomas [Vis alle 7 forfattere av denne artikkelen] (2022). Postprandial Effects of Salmon Fishmeal and Whey on Metabolic Markers in Serum and Gene Expression in Liver Cells. Nutrients. ISSN 2072-6643. 14(8). doi: 10.3390/nu14081593. Fulltekst i vitenarkiv
  • Norheim, Frode Amador; Chella Krishnan, Karthickeyan; Bjellaas, Thomas; Vergnes, Laurent; Pan, Calvin & Parks, Brian W. [Vis alle 18 forfattere av denne artikkelen] (2021). Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis. Molecular Systems Biology. ISSN 1744-4292. 17. doi: 10.15252/msb.20209684. Fulltekst i vitenarkiv
  • Bodin, Johanna Eva; Thorstensen, Tage; Alsheikh, Muath K; Basic, Dean; Edvardsen, Rolf Brudvik & Dalen, Knut Tomas [Vis alle 41 forfattere av denne artikkelen] (2021). Genome editing in food and feed production – implications for risk assessment. Scientific Opinion of the Scientific Steering Committee of the Norwegian Scientific Committee for Food and Environment. VKM Report. ISSN 2535-4019. 2021(18). Fulltekst i vitenarkiv
  • Hustad, Kristin Solheim; Ottestad, Inger Olaug; Hjorth, Marit; Dalen, Knut Tomas; Sæther, Thomas & Sheikh, Navida Akhter [Vis alle 9 forfattere av denne artikkelen] (2021). No effect of salmon fish protein on 2-h glucose in adults with increased risk of type 2 diabetes: a randomised controlled trial. British Journal of Nutrition. ISSN 0007-1145. 126(9), s. 1304–1313. doi: 10.1017/S0007114521000040. Fulltekst i vitenarkiv
  • Doncheva, Atanaska Ivanova; Norheim, Frode Amador; Hjorth, Marit; Grujic, Mirjana; Paivandy, Aida & Dankel, Simon N [Vis alle 14 forfattere av denne artikkelen] (2021). Serglycin Is Involved in Adipose Tissue Inflammation in Obesity. Journal of Immunology. ISSN 0022-1767. 208(1), s. 121–132. doi: 10.4049/jimmunol.2100231.
  • Li, Yuchuan; Khanal, Prabhat; Norheim, Frode; Hjorth, Marit; Bjellaas, Thomas & Drevon, Christian A [Vis alle 9 forfattere av denne artikkelen] (2021). Plin2 deletion increases cholesteryl ester lipid droplet content and disturbs cholesterol balance in adrenal cortex. Journal of Lipid Research. ISSN 0022-2275. 62. doi: 10.1016/J.JLR.2021.100048. Fulltekst i vitenarkiv
  • Li, Yuchuan; Torp, May-Kristin; Norheim, Frode; Khanal, Prabhat; Kimmel, Alan R. & Stensløkken, Kåre-Olav [Vis alle 8 forfattere av denne artikkelen] (2020). Isolated Plin5-deficient cardiomyocytes store less lipid droplets than normal, but without increased sensitivity to hypoxia . Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1866(4). doi: 10.1016/j.bbalip.2020.158873. Fulltekst i vitenarkiv
  • Henjum, Sigrun; Brantsæter, Anne Lise; Holvik, Kristin; Lillegaard, Inger Therese Laugsand; Mangschou, Bente & Parr, Christine Louise [Vis alle 14 forfattere av denne artikkelen] (2020). Benefit and risk assessment of iodization of household salt and salt used in bread and bakery products. Scientific opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food and Environment. VKM Report. ISSN 2535-4019. 2020(5), s. 1–312. Fulltekst i vitenarkiv
  • Raheel, Tayyaba Qureshi; Sørensen, Christina; Berghuis, Paul; Jensen, Vidar; Dobszay, Marton B. & Farkas, Tamás [Vis alle 14 forfattere av denne artikkelen] (2019). The glutamine transporter Slc38a1 regulates GABAergic neurotransmission and synaptic plasticity. Cerebral Cortex. ISSN 1047-3211. 29(12), s. 5166–5179. doi: 10.1093/cercor/bhz055. Fulltekst i vitenarkiv
  • Mardani, Ismena; Dalen, Knut Tomas; Miljanovic, Azra; Drevinge, Christina; Ståhlman, Marcus & Klevstig, Martina [Vis alle 17 forfattere av denne artikkelen] (2019). Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart. Scientific Reports. ISSN 2045-2322. 9(1). doi: 10.1038/s41598-019-43335-y. Fulltekst i vitenarkiv
  • Yaddehi Gamage, Thilini Hansamali Gamage; Gunnes, Gjermund; Lee, Robert Hugh; Louch, William Edward; Holmgren, Asbjørn & Bruton, Joseph D. [Vis alle 19 forfattere av denne artikkelen] (2018). STIM1 R304W causes muscle degeneration and impaired platelet activation in mice. Cell Calcium. ISSN 0143-4160. 76, s. 87–100. doi: 10.1016/j.ceca.2018.10.001. Fulltekst i vitenarkiv
  • Lee, Yun K.; Sohn, Jee Hyung; Han, Ji Seul; Park, Yoon Jeong; Jeon, Yong Geun & Ji, Yul [Vis alle 10 forfattere av denne artikkelen] (2018). Perilipin 3 deficiency stimulates thermogenic Beige adipocytes through PPARa activation. Diabetes. ISSN 0012-1797. 67(5), s. 791–804. doi: 10.2337/db17-0983.
  • Feng, Yuan Zeng; Lund, Jenny; Li, Yuchuan; Knabenes, Irlin; Bakke, Siril Skaret & Kase, Eili Tranheim [Vis alle 11 forfattere av denne artikkelen] (2017). Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation. Journal of Lipid Research. ISSN 0022-2275. 58(11), s. 2147–2161. doi: 10.1194/jlr.M079764. Fulltekst i vitenarkiv
  • Fan, Qiong; Nørgaard, Rikke Christine; Bindesbøll, Christian; Lucas, Christin; Dalen, Knut Tomas & Babaie, Eshrat [Vis alle 10 forfattere av denne artikkelen] (2017). LXR? regulates hepatic ChREBP? activity and lipogenesis upon glucose, but not fructose feeding in mice. Nutrients. ISSN 2072-6643. 9(7). doi: 10.3390/nu9070678.
  • Haj Yasein, Nadia; Berg, Ole; Jerneren, Fredrik; Refsum, Helga; Nebb, Hilde Irene & Dalen, Knut Tomas (2017). Cysteine deprivation prevents induction of peroxisome proliferator-activated receptor gamma-2 and adipose differentiation of 3T3-L1 cells. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1862(6), s. 623–635. doi: 10.1016/j.bbalip.2017.02.009.
  • Drevinge, Christina; Dalen, Knut Tomas; Mannila, Maria Nastase; Täng, Margareta Scharin; Ståhlman, Marcus & Klevstig, Martina [Vis alle 30 forfattere av denne artikkelen] (2016). Perilipin 5 is protective in the ischemic heart. International Journal of Cardiology. ISSN 0167-5273. 219, s. 446–454. doi: 10.1016/j.ijcard.2016.06.037.
  • Dahl, John Arne; Jung, Inkyung; Aanes, Håvard; Greggains, Gareth; Manaf, Adeel & Lerdrup, Mads [Vis alle 20 forfattere av denne artikkelen] (2016). Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition. Nature. ISSN 0028-0836. 537(7621), s. 548–552. doi: 10.1038/nature19360.
  • Pourteymour, Shirin; Lee, Sindre; Langleite, Torgrim Mikal; Eckardt, Kristin; Hjorth, Marit & Bindesbøll, Christian [Vis alle 11 forfattere av denne artikkelen] (2015). Perilipin 4 in human skeletal muscle: localization and effect of physical activity. Physiological Reports. ISSN 2051-817X. 3:e12481(8), s. 1–15. doi: 10.14814/phy2.12481.
  • Norheim, Frode; Hjorth, Marit; Langleite, Torgrim Mikal; Lee, Sindre; Holen, Torgeir & Bindesbøll, Christian [Vis alle 13 forfattere av denne artikkelen] (2014). Regulation of angiopoietin-like protein 4 Production during and after exercise. Physiological Reports. ISSN 2051-817X. 2(8). doi: 10.14814/phy2.12109.
  • Telle, Vibeke Helen; Halvorsen, Bente ; Dalen, Knut Tomas; Narverud, Ingunn; Rao, Nima & Granlund, L [Vis alle 8 forfattere av denne artikkelen] (2013). Altered expression of genes involved in lipid metabolism in obese subjects with unfavourable phenotype. Genes & Nutrition. ISSN 1555-8932. 8(4), s. 425–434. doi: 10.1007/s12263-012-0329-z.
  • Haj-Yasein, Nadia Nabil; Dalen, Knut Tomas; Berg, Ole; Bastani, Nasser Ezzatkhah; Refsum, Helga & Nebb, Hilde Irene (2013). Low Cysteine Interferes With PPARγ Activity And Reduces Adipocyte Differentiation. The Journal of Inherited Metabolic Disease (JIMD). ISSN 0141-8955. 36. doi: 10.1007/s10545-013-9631-1.
  • Bindesbøll, Christian; Berg, Ole; Arntsen, Borghild M; Nebb, Hilde Irene & Dalen, Knut Tomas (2013). Fatty acids regulate perilipin5 in muscle by activating PPARdelta. Journal of Lipid Research. ISSN 0022-2275. 54(7), s. 1949–1963. doi: 10.1194/jlr.M038992.
  • Norheim, Frode; Gjelstad, Ingrid Merethe Fange; Hjorth, Marit; Vinknes, Kathrine; Langleite, Torgrim Mikal & Holen, Torgeir [Vis alle 12 forfattere av denne artikkelen] (2012). Molecular nutrition research - the modern way of performing nutritional science. Nutrients. ISSN 2072-6643. 4(12), s. 1898–1944. doi: 10.3390/nu4121898.
  • Hsieh, Kai; Lee, Yen-Kun; Londos, C; Raaka, BM; Dalen, Knut Tomas & kimmel, Alan (2012). Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets. Journal of Cell Science. ISSN 0021-9533. 125(17), s. 4067–4076. doi: 10.1242/jcs.104943.
  • Wang, H; Bell, H; Sreenevasan, u; Hu, H; Liu, J & Dalen, Knut Tomas [Vis alle 13 forfattere av denne artikkelen] (2011). Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein. Journal of Biological Chemistry. ISSN 0021-9258. 286(6), s. 15707–15715.
  • Weedon, Mina Susanne; Dalen, Knut Tomas; Solaas, Karianne; Staff, Anne Cathrine; Duttaroy, Asim K. & Nebb, Hilde Irene (2010). Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells. Journal of Lipid Research. ISSN 0022-2275. 51(7), s. 1886–1896. doi: 10.1194/jlr.M004978.
  • Qin, Yan; Dalen, Knut Tomas; Gustafsson, Jan Åke & Nebb, Hilde Irene (2009). Regulation of hepatic fatty acid elongase 5 by LXRalpha-SREBP-1c. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1791(2), s. 140–147. doi: 10.1016/j.bbalip.2008.12.003.
  • Wang, H; hu, l; Dalen, Knut Tomas; dorward, h; Marcinkiewicz, a & Russell, d [Vis alle 13 forfattere av denne artikkelen] (2009). Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins. Journal of Biological Chemistry. ISSN 0021-9258. 46(284), s. 32116–32125.
  • Dalen, Knut Tomas; Dahl, Tuva Børresdatter; Holter, Elin; Arntsen, Borghild M; Londos, C & Sztalryd, C [Vis alle 7 forfattere av denne artikkelen] (2007). LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. ISSN 1388-1981. 1771, s. 210–227. doi: 10.1016/j.bbalip.2006.11.011.
  • Zernichow, L; Dalen, Knut Tomas; Dalen, L.; Prydz, K; Winberg, Jan-Olof & Kolset, S O (2006). Secretion of proteases in serglycin transfected Madin-Darby canine kidney cells. The FEBS Journal. ISSN 1742-464X. 273.
  • Tobin, Kari Anne Risan; Harsem, NK; Dalen, Knut Tomas; Staff, AC; Nebb, Hilde Irene & Duttaroy, Asim K. (2006). Regulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell line. Journal of Lipid Research. ISSN 0022-2275. 47, s. 815–823.
  • Dalen, Knut Tomas; Ulven, Stine Marie; Arntsen, Borghild M; Solaas, Karianne & Nebb, Hilde Irene (2006). PPAR alpha activators and fasting induce the expression of adipose differentiation-related protein in liver. Journal of Lipid Research. ISSN 0022-2275. 47, s. 931–943.
  • Wang, Line M. Grønning; Tingsabadh, R; Hardy, K; Dalen, Knut Tomas; Jat, PS & Gnudi, L [Vis alle 7 forfattere av denne artikkelen] (2006). Glucose induces increases in levels of the transcriptional repressor Id2 via the hexosamine pathway. American Journal of Physiology. Endocrinology and Metabolism. ISSN 0193-1849. 290(4), s. 599–606.
  • Ulven, Stine Marie; Dalen, Knut Tomas; Gustafsson, JA & Nebb, Hilde Irene (2005). LXR is crucial in lipid metabolism. Prostaglandins, Leukotrienes and Essential Fatty Acids. ISSN 0952-3278. 73, s. 59–63.
  • Haugen, Fred; Zahid, N; Dalen, Knut Tomas; Hollung, K; Nebb, Hilde Irene & Drevon, Christian A (2005). Resistin expression in 3T3-L1 adipocytes is reduced by arachidonic acid. Journal of Lipid Research. ISSN 0022-2275. 46.
  • Dalen, Knut Tomas; Schoonjans, K; Ulven, SM; Weedon, Mina Susanne; Bentzen, Trine Gjesti & Koutnikova, H [Vis alle 8 forfattere av denne artikkelen] (2004). Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma. Diabetes. ISSN 0012-1797. 53(5), s. 1243–1252.
  • Ulven, Stine Marie; Dalen, Knut Tomas; Gustafsson, Jan-Åke & Nebb, Hilde Irene (2004). Tissue-specific autoregulation of the LXRalpha gene facilitates induction of apoE in mouse adipose tissue. Journal of Lipid Research. ISSN 0022-2275. 45(11), s. 2052–2062.
  • Juvet, Lene Kristine; Schuster, Gertrud U.; Dalen, Knut Tomas; Tobin, Kari Anne Risan; Hollung, Kristin & Haugen, Fred [Vis alle 8 forfattere av denne artikkelen] (2003). On the role of liver X receptors in lipid accumulation in adipocytes. Molecular Endocrinology. ISSN 0888-8809. 17, s. 172–182.
  • Dalen, Knut Tomas; Ulven, Stine Marie & Nebb, Hilde Irene (2003). Expresssion of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha. Journal of Biological Chemistry. ISSN 0021-9258. 278(48), s. 48283–48291.
  • Alvik, Astrid & Dalen, Knut (2002). Det føtale alkoholsyndrom - FAS. I Gjærum, Bente & Ellertsen, Bjørn (Red.), Hjerne og atferd; Utviklingsforstyrrelser hos barn og ungdom i et nevrobiologisk perspektiv. Gyldendal Akademisk. ISSN 82-05-30434-3. s. 333–350.
  • Prydz, Kristian & Dalen, Knut Tomas (2000). Synthesis and sorting of proteoglycans. Journal of Cell Science. ISSN 0021-9533. 113, s. 193–205.

Se alle arbeider i Cristin

  • Jez, Joseph & Dalen, Knut Tomas (2021). Encyclopedia of Biological Chemistry III (Third Edition). Elsevier. ISBN 978-0-12-822040-5. 500 s.
  • Dalen, Knut Tomas; londos, constantine & kimmel, Alan (2011). Adipocyte Fat Mobilization: The Regulatory Roles of Perilipin 1, Adipose Triglyceride Lipase, and Hormone Sensitive Lipase. Elsevier. ISBN 978-0-12-443710-4.

Se alle arbeider i Cristin

  • Bodin, Johanna Eva; Aakre, Inger; Alexander, Jan; Mangschou, Bente; Parr, Christine Louise & Andersen, Lene Frost [Vis alle 15 forfattere av denne artikkelen] (2023). Risk assessment of hyaluronic acid in food supplements . VKM Report. ISSN 2535-4019. 13, s. 1–70. Fulltekst i vitenarkiv
  • Doncheva, Atanaska Ivanova; Li, Yuchuan; Khanal, Prabhat & Dalen, Knut Tomas (2022). Perilipin 2 regulates hepatic lipid content and lipid droplet size during fasting .
  • Hjorth, Marit; Doncheva, Atanaska Ivanova; Norheim, Frode Amador; Ulven, Stine Marie; Holven, Kirsten Bjørklund & Sæther, Thomas [Vis alle 7 forfattere av denne artikkelen] (2022). Consumption of salmon fishmeal increases hepatic cholesterol content in obese C57BL/6J mice .
  • Dalen, Knut Tomas (2022). Perilipins and regulation of intracellular lipid droplets.
  • Dalen, Knut Tomas & Kimmel, Alan R (2021). Lipids | Adipocyte Fat Mobilization: Regulatory Functions Involving Perilipin 1, Adipose Triglyceride Lipase, and Hormone-Sensitive Lipase, Encyclopedia of Biological Chemistry III (Third Edition). Elsevier. ISSN 978-0-12-822040-5. s. 492–500. doi: 10.1016/B978-0-12-819460-7.00337-6.
  • Dalen, Knut Tomas (2021). Lipid droplets and transgenic animals.
  • Holven, Kirsten Bjørklund; Sæther, Thomas; Hjorth, Marit; Dalen, Knut Tomas; Ulven, Stine Marie & Ottestad, Inger [Vis alle 7 forfattere av denne artikkelen] (2019). Kan fisk utnyttes enda mer og samtidig fremme folkehelsen? Norsk tidsskrift for ernæring (NTFE). ISSN 1503-5034. 17(2), s. 20–22.
  • Andersson, Linda; Drevinge, Christina; Mardani, Ismena; Dalen, Knut Tomas; Ståhlman, Marcus & Klevstig, Martina [Vis alle 18 forfattere av denne artikkelen] (2017). Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse hearts. International Journal of Biochemistry and Cell Biology. ISSN 1357-2725. 91, s. 9–13. doi: 10.1016/j.biocel.2017.07.021.
  • Feng, Yuan Zeng; knabenes, Irlin Knivsland; Bakke, Siril S.; Lund, Jenny; Lee, Y.K. & kimmel, Alan [Vis alle 9 forfattere av denne artikkelen] (2015). Increased lipid oxidation and decreased lipid storage in myotubes lacking the lipid droplet binding protein perilipin2.
  • Catterall, Tara Cherie; Johnson, Inna; Khan, Shaista; Jermstad, Ingunn; Nesse, Gaute & Klungland, Arne [Vis alle 7 forfattere av denne artikkelen] (2015). The Norwegian Transgenic Centre.
  • Bindesbøll, Christian; Berg, Ole; Arntsen, Borghild M; Nebb, Hilde Irene & Dalen, Knut Tomas (2014). Fatty acids regulate perilipin5 in muscle by activating PPARdelta.
  • Dalen, Knut Tomas; Haj-Yasein, Nadia Nabil; Berg, Ole; Refsum, Helga & Nebb, Hilde Irene (2014). Cysteine and adipocyte differentiation.
  • Dalen, Knut Tomas (2014). Transgenic techniques provided by the Norwegian Transgenic Centre.
  • Khan, Shaista; Jermstad, Ingunn; Catterall, Tara Cherie; Nesse, Gaute; Klungland, Arne & Dalen, Knut Tomas (2014). The Norwegian Transgenic Centre.
  • Feng, Yuan Zeng; knabenes, Irlin Knivsland; Lund, Jenny; Lee, Y.K.; kimmel, Alan & Thoresen, G. Hege [Vis alle 8 forfattere av denne artikkelen] (2014). Increased lipid oxidation and decreased lipid storage in myotubes lacking perilipin2.
  • Bindesbøll, Christian; Fan, Qiong; Sæther, Thomas; Dalen, Knut Tomas; Nebb, Hilde Irene & Grønning-Wang, Line Mariann (2013). Nuclear receptors as targets for treatment and prevention of metabolic diseases.
  • Telle-Hansen, Vibeke; Halvorsen, Bente ; Dalen, Knut Tomas; Narverud, Ingunn; Wesseltoft-Rao, Nima & Granlund, Linda [Vis alle 8 forfattere av denne artikkelen] (2013). Altered expression of genes involved in lipid metabolism in obese subjects with unfavourable phenotype.
  • Dalen, Knut Tomas (2011). Lipid droplet binding proteins and lipid accumulation.
  • Dalen, Knut Tomas; Londos, C & Nebb, Hilde Irene (2009). PAT proteins and their function on intracellular lipid droplets.
  • Dalen, Knut Tomas; Ulven, Stine Marie; Weedon, Mina Susanne; Bentzen, Trine Gjesti & Nebb, Hilde Irene (2004). The perioxisome proliferator-activated receptor gamma coordinately regulates the members of the lipid droplet associating protein gene family.
  • Dalen, Knut Tomas; Ulven, Stine Marie & Nebb, Hilde Irene (2003). Insulin regulation of the insulin responsive glucose transporter (GLUT4) in adipocytes is dependent on Liver X receptor alpha.
  • Dalen, Knut Tomas; Weedon, Mina Susanne; Bentzen, Trine Gjesti & Nebb, Hilde Irene (2002). The nuclear receptor PPARgamma regulates the expression of S3-12 and other members of the lipid droplet binding protein gene family in adipocytes.
  • Prydz, Kristian; Vuong, Tram Thu; Dalen, Knut Tomas; Kulseth, M. A. & Kolset, Svein Olav (1997). Chondroitin sulfate glycosaminoglycan chains contain apical sorting information in epithelial MDCK cells.
  • Løvik, Martinus; Dahl, Lisbeth; Mangschou, Bente; Ulven, Stine Marie; Andersen, Lene Frost & Dalen, Knut Tomas [Vis alle 10 forfattere av denne artikkelen] (2019). Assessment of dietary intake of fluoride and maximum limits of fluoride in food supplements. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food and Environment. Norwegian Scientific Committee for Food and Environment (VKM). ISSN 978-82-8259-328-1. Fulltekst i vitenarkiv
  • Meadow, Richard; Asare, Nana Yaa Ohene; Dalen, Knut Tomas; Finne, Merethe Aasmo; Junttila, Olavi & Kirkendall, Lawrence R. [Vis alle 13 forfattere av denne artikkelen] (2017). Risk assessment of insect-resistant and herbicide-tolerant genetically modified maize Bt11 for cultivation, import, processing, food and feed uses under Directive 2001/18/EC and Regulation (EC). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-279-6. Fulltekst i vitenarkiv
  • Meadow, Richard; Asare, Nana Yaa Ohene; Finne, Merethe Aasmo; Junttila, Olavi; Kirkendall, Lawrence R. & Måren, Inger Elisabeth [Vis alle 13 forfattere av denne artikkelen] (2017). Risk assessment of insect-resistant and herbicide-tolerant genetically modified maize 1507 for cultivation, import, processing, food and feed uses under Directive 2001/18/EC (C/ES/01/01, C/NL/00/10) and Regulation (EC) No 1829/2003 (EFSA/GMO/NL/2004/02, EFSA/GMO/RX/1507). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-278-9. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Bakke, Anne Marie; Dahl, Knut Helkås; Junttila, Olavi; Mikalsen, Arne & Sipinen, Ville Erling [Vis alle 14 forfattere av denne artikkelen] (2016). Final health and environmental risk assessment of genetically modified cotton 281-24-236 x 3006-210-23 (MXB-13). Scientific opinion on insect-resistant and glufosinate-tolerant, genetically modified MXB-13 from Dow AgroSciences for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (Application EFSA/GMO/NL/2005/16). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-198-0. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Bakke, Anne Marie; Junttila, Olavi; Mikalsen, Arne; Sipinen, Ville Erling & Vikse, Rose [Vis alle 14 forfattere av denne artikkelen] (2016). Final health and environmental risk assessment of genetically modified cotton GHB614. Scientific opinion on glyphosate-tolerant, genetically modified cotton GHB614 from Bayer CropScience for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (Application EFSA/GMO/NL/2008/51). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-199-7. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Bakke, Anne Marie; Junttila, Olavi; Mikalsen, Arne; Sipinen, Ville Erling & Vikse, Rose [Vis alle 14 forfattere av denne artikkelen] (2016). Final health and environmental risk assessment of genetically modified LLcotton25. Scientific opinion on glufosinate-tolerant, genetically modified LLcotton25 from Bayer CropScience for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (Application EFSA/GMO/NL/2005/13). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-200-0. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Sipinen, Ville Erling; Finne, Merethe Aasmo; Brandtzæg, Per; Dahl, Knut Helkås & Dalen, Knut Tomas [Vis alle 13 forfattere av denne artikkelen] (2016). Risk assessment of genetically modified carnation SHD-27531-4. Scientific opinion on genetically modified carnation SHD-27531-4 from Suntory Holdings Ltd. with modified petal colour for import as cut flowers for ornamental use under Part C of Directive 2001/18/EC (Application C/NL/13/01). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-224-6. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Sipinen, Ville Erling; Finne, Merethe Aasmo; Brandtzæg, Per; Dahl, Knut Helkås & Dalen, Knut Tomas [Vis alle 13 forfattere av denne artikkelen] (2016). Risk assessment of genetically modified carnation FLO-40685-2. Scientific opinion on genetically modified carnation FLO-40685-2 from Suntory Holdings Ltd. with modified petal colour for import as cut flowers for ornamental use under Part C of Directive 2001/18/EC (Application C/NL/13/02). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-225-3. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Bakke, Anne Marie; Dahl, Knut Helkås; Dalen, Knut Tomas; Finne, Merethe Aasmo & Mikalsen, Arne [Vis alle 14 forfattere av denne artikkelen] (2015). Food/feed and environmental risk assessment of herbicide tolerant genetically modified soybean A2704-12 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (EFSA/GMO/NL/2005/18). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-162-1. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Bakke, Anne Marie; Dahl, Knut Helkås; Dalen, Knut Tomas; Finne, Merethe Aasmo & Mikalsen, Arne [Vis alle 14 forfattere av denne artikkelen] (2015). Food/feed and environmental risk assessment of herbicide tolerant genetically modified soybean A5547-127 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (EFSA/GMO/NL/2008/52). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-163-8. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Bakke, Anne Marie; Dahl, Knut Helkås; Dalen, Knut Tomas; Finne, Merethe Aasmo & Mikalsen, Arne [Vis alle 14 forfattere av denne artikkelen] (2015). Final health and environmental risk assessment of genetically modified soybean MON 89788. Scientific opinion on herbicide tolerant, genetically modified soybean MON 89788 from Monsanto Company for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (Application EFSA/GMO/NL/2006/36). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety . Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-164-5. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Asare, Nana Yaa Ohene; Bakke, Anne Marie; Dahl, Knut Helkås; Dalen, Knut Tomas & Nielsen, Kaare Magne [Vis alle 13 forfattere av denne artikkelen] (2015). Final health and environmental risk assessment of genetically modified soybean 356043. Scientific opinion on herbicide tolerant, genetically modified soybean 356043 from Pioneer Hi-Bred for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (Application EFSA/GMO/UK/2007/43). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-168-3. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Asare, Nana Yaa Ohene; Bakke, Anne Marie; Dahl, Knut Helkås; Dalen, Knut Tomas & Nielsen, Kaare Magne [Vis alle 13 forfattere av denne artikkelen] (2015). Final health and environmental risk assessment of genetically modified soybean MON 87701. Scientific opinion on insect resistant, genetically modified soybean MON 87701 from Monsanto for food and feed uses, import and processing under Regulation (EC) No 1829/2003 (Application EFSA/GMO/BE/2010/79). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-169-0. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Asare, Nana Yaa Ohene; Bakke, Anne Marie; Finne, Merethe Aasmo; Jevnaker, Anne Marthe & Junttila, Olavi [Vis alle 15 forfattere av denne artikkelen] (2015). Final health and environmental risk assessment of genetically modified carnation Moonlite 123.2.38. Scientific opinion on genetically modified carnation Moonlite 123.2.38 from Florigene with modified petal colour for import as cut flowers for ornamental use under Part C of Directive 2001/18/EC (Application C/NL/04/02). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegoan Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-170-6. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Asare, Nana Yaa Ohene; Bakke, Anne Marie; Finne, Merethe Aasmo; Jevnaker, Anne Marthe & Junttila, Olavi [Vis alle 15 forfattere av denne artikkelen] (2015). Final health and environmental risk assessment of genetically modified carnation Moonaqua 123.8.12. Scientific opinion on genetically modified carnation Moonaqua 123.8.12 from Florigene with modified petal colour for import as cut flowers for ornamental use under Part C of Directive 2001/18/EC (Application C/NL/06/01). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-171-3. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Asare, Nana Yaa Ohene; Bakke, Anne Marie; Finne, Merethe Aasmo; Jevnaker, Anne Marthe & Junttila, Olavi [Vis alle 15 forfattere av denne artikkelen] (2015). Final health and environmental risk assessment of genetically modified carnation Moonberry IFD-25958-3. Scientific opinion on genetically modified carnation Moonberry IFD-25958-3 from Florigene with modified petal colour for import as cut flowers for ornamental use under Part C of Directive 2001/18/EC (Application C/NL /09/01). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-172-0. Fulltekst i vitenarkiv
  • Andreassen, Åshild Kristine; Asare, Nana Yaa Ohene; Bakke, Anne Marie; Finne, Merethe Aasmo; Jevnaker, Anne Marthe & Junttila, Olavi [Vis alle 15 forfattere av denne artikkelen] (2015). Final health and environmental risk assessment of genetically modified carnation Moonvelvet IFD-26407-2. Scientific opinion on genetically modified carnation Moonvelvet IFD-26407-2 from Florigene with modified petal colour for import as cut flowers for ornamental use under Part C of Directive 2001/18/EC (Application C/NL/09/02). Opinion of the Panel on Genetically Modified Organisms of the Norwegian Scientific Committee for Food Safety. Norwegian Scientific Committee for Food Safety (VKM). ISSN 978-82-8259-173-7. Fulltekst i vitenarkiv

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Publisert 13. apr. 2011 10:35 - Sist endret 11. jan. 2024 16:31

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