Cost-Effectiveness of Early Asymptomatic Biomarker Detection and Monitoring in Patients with Alzheimer’s Disease: An Explorative Scenario Analysis

Pre-symptomatic intervention without biomarker inclusion has already proven to be cost-effective in Alzheimer patients in the past, but there is a need for further research (Barnett, Lewis, Blackwell & Taylor, 2014; Alzheimer’s Association, 2018). Blood biomarkers seem to be promising to detect onset of AD pre-symptomatic, however, it is often not tested in (human) clinical trials. Therefore, an early economic evaluation is necessary to determine: what is the potential cost-effectiveness of blood test biomarkers? What test characteristics need to be identified in order for blood test biomarkers to be considered cost-effective? What are the added benefits and costs of including blood biomarkers as part of the current diagnostic pathway? The current diagnostic pathway here using MRI and fluorodeoxyglucose PET, due to symptoms. Lastly, what are the long term added benefits and costs of blood test biomarkers for diagnosis and monitoring AD?

Prosjektbeskrivelse med vedlegg

Disse dokumentene er kun synlige for prosjektleder, enhetens leder og forskningsadministrasjon.

TSD

  • Nei
  • Begrunnelse: Data fra literaturen

Biobank

  • Nei

Godkjenninger

Prosjektet har ingen godkjenninger

Prosjektleder / prosjektansvarlig ved UiO

Eline Aas

Ansvarlig enhet

Avdeling for helseledelse og helseøkonomi

Prosjekttype

  • Studentprosjekt – Bachelor-, master- eller spesialistoppgave

Helsefaglig forskning

  • Ja

Personopplysninger

  • Nei

Tidsperiode

  • Start: desember 2019
  • Slutt: juli 2020