Antimicrobial resistance in resource limited countries and migrant populations.
Development and spread of antimicrobial resistance (AMR) is occurring everywhere and compromises our ability to treat infectious diseases and undermines advances in medicine and health. Improper use of antimicrobials, lack of microbiological diagnostic services, poor sanitation, shortage of clean water and interpersonal spread are key factors in the development and dissemination of resistant bacterial strains. All these factors are common in resource-limited countries.
Resistant bacteria do not respect borders and are spread with people, products, livestock and animals. Increased AMR in any part of the world, and particularly in areas with high export or emigration and in popular tourist-destinations, is of global concern.
Sub-Sahara Africa is a region where surveillance systems and data regarding AMR is lacking. Most of the African migrants arriving in Norway are of Eritrean, Somali and Ethiopian origin.
The aim of this project is to study the colonization of multi-drug resistant gram-negative bacteria (MDRGN) in migrants arriving in Norway from Eritrea, Somalia and Ethiopia. For comparison, surveys to assess AMR/MDRGN prevalence and colonization in Jimma, Ethiopia, will be done. The rate and extent of clearance in MDRGN-positive migrants arriving in Norway will also be studied, and genetic analysis of the bacteria will be performed.