FRM-KJM5050 – Bioanalytical Chemistry I: Advanced Separation Methods and Bioanalysis
Schedule, syllabus and examination date
Teaching and exams spring 2022
In light of the most recent infection control regulations, we will at the start of the spring semester 2022 increase our online teaching, while we at the same time try to maintain in-person teaching where this is possible. We hope to go back to more in-person teaching later on in the semester. You will be informed about any changes in teaching or examinations on the semester page, in Canvas or through your regular channels.
Read more about postponed exams for the autumn semester 2021.
FRM-KJM5050 focuses on the most important aspects in all steps of an analytical method to determine biological active compounds (endogeneous compounds, environmental pollution, drugs etc.) in various biological matrices (like serum, urine, cell culture) and environmental samples (water).
The course discusses the following topics:
- composition of various sample matrices (biological and environmental) together with their analytical limitations
- most used sample preparation techniques like liquid-liquid and solid phase extraktion (both off-line and on-line)
- advanced liquid chromatography, column technology, stationary phases and miniaturization
- LC-MS: ionization, analysis, detection and mass spectrum interpretation
- LC-MS based doping analysis
Admission to the course
Students at UiO must apply for courses in StudentWeb.
The course is primarily open to students who have been admitted to the Department of Pharmacy and master study in Chemistry at the University of Oslo.
Chemistry students apply for admittance to the course and exam in StudentWeb.
Pharmacy students need to contact study administration to apply for admittance to the course and exam.
If there is space available then others may also apply to take the course as long as their academic background is adequate.
International applicants, if you are not already enrolled as a student at UiO, please see our information about admission requirements and procedures for international applicants.
Recommended previous knowledge
Analytical chemistry corresponding to FRM2010 – Quality Control of Pharmaceutical ingredients (discontinued) and FRM3030 – Use of Drugs, Part III (discontinued) (for pharmacy students) or KJM2400 – Analytical Chemistry I and KJM3400 – Analytical Chemistry II - Separation Methods (for chemistry students).
- 10 credits overlap with FRM-KJM9050 – Bioanalytical Chemistry I: Advanced Separation Methods and Bioanalysis.
- 10 credits overlap with FARM-KJM5010 – Bioanalytical chemistry I: Advanced Bioanalysis for Life Sciences.
- 10 credits overlap with FARM-KJM9010 – Bioanalytical chemistry I: Advanced Bioanalysis for Life Science.
- 5 credits overlap with FRM9310 – Biomedical analysis (discontinued).
- 5 credits overlap with FRM5310 – Biomedical analysis (discontinued).
- 5 credits overlap with KJM5460 – Analytical chemistry. Separation methods II (discontinued).
- 5 credits overlap with KJM9460 – Analytical Chemistry, Separation Methods II (discontinued).
There will be 11 days of lectures and colloquia. Together with a fellow student (or alone if you prefer), you will present a recent scientific article that will be handed out on the course. The presentation has to be approved before you can attend the final exam. There will be no laboratory training.
Access to teaching
A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.
The course can be canceled if the number of students enrolled is low.
Final exam counts 100 %. Depending on the number of students, the final exam will either be a 4 hours long written digital exam or a 45 minutes long oral exam.
The presentation has to be approved before you can attend the final exam.
The written examination is conducted in the digital examination system Inspera. You will need to familiarize yourself with the digital examination arrangements in Inspera.
Withdrawal from an examination
It is possible to take the exam up to 3 times. If you withdraw from the exam after the deadline or during the exam, this will be counted as an examination attempt. It will also be counted as one of the three attempts to sit the exam for this course, if you sit the exam for one of the following courses:
Examination support material
As of 1 August, 2016, the use of own calculators is no longer permitted. Casio FX-991EX calculators are handed out to all exam candidates at the beginning of the exam.
Language of examination
You may submit your response in Norwegian, Swedish, Danish or English. If you would prefer to have the exam text in English, you may apply to the course administrators.
Grades are awarded on a scale from A to F, where A is the best grade and F is a fail. Read more about the grading system.
Resit an examination
This course offers both postponed and resit of examination. Read more: