FRM-KJM9050 – Bioanalytical Chemistry I: Advanced Separation Methods and Bioanalysis

Schedule, syllabus and examination date

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Changes in the course due to coronavirus

Autumn 2020 the exams of most courses at the MN Faculty will be conducted as digital home exams or oral exams, using the normal grading scale. The semester page for your course will be updated with any changes in the form of examination.

See general guidelines for examination at the MN Faculty autumn 2020.

Course content

FRM-KJM9050 focuses on the most important aspects in all steps of an analytical method to determine biological active compounds (endogeneous compounds, environmental pollution, drugs etc.) in various biological matrices (like serum, urine, cell culture) and environmental samples (surface water).

Learning outcome

The course discusses the following topics:

  • composition of various sample matrices (biological and environmental) together with their analytical limitations
  • most used sample preparation techniques like liquid-liquid and solid phase extraction (both off-line and on-line)
  • advanced liquid chromatography, column technology, stationary phases and miniaturization
  • LC-MS: ionization, analysis, detection and mass spectrum interpretation
  • LC-MS based doping analysis
  • present and discuss scientific articles in the field

Admission to the course

PhD candidates from the University of Oslo should apply for classes and register for examinations through Studentweb.

If a course has limited intake capacity, priority will be given to PhD candidates who follow an individual education plan where this particular course is included. Some national researchers’ schools may have specific rules for ranking applicants for courses with limited intake capacity.

PhD candidates who have been admitted to another higher education institution must apply for a position as a visiting student within a given deadline.

Analytical chemistry corresponding to FRM2010 – Quality Control of Pharmaceutical ingredients and FRM3030 – Use of Drugs, Part III (for pharmacy students) or KJM2400 – Analytical Chemistry I and KJM3400 – Analytical Chemistry II - Separation Methods (for chemistry students).

Overlapping courses


There will be 11 days of lectures and colloquia. PhD students need to present and discuss at least two recent scientific publications which will be handed out on the course (mandatory). The presentations have to be approved before you can attend the final exam. There will be no laboratory training.

Access to teaching

A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.

The course can be canceled if the number of students enrolled is low.


Final exam counts 100 %. Depending on the number of students, the final exam will either be a 4 hours long written digital exam or a 45 minutes long oral exam.

The presentation has to be approved before you can attend the final exam.

Digital examination

The written examination is conducted in the digital examination system Inspera. You will need to familiarize yourself with the digital examination arrangements in Inspera.

Read more about written examinations using Inspera.

Withdrawal from an examination

It is possible to take the exam up to 3 times. If you withdraw from the exam after the deadline or during the exam, this will be counted as an examination attempt. It will also be counted as one of the three attempts to sit the exam for this course, if you sit the exam for one of the following courses:

Examination support material

As of 1 August, 2016, the use of own calculators is no longer permitted. Casio FX-991EX calculators are handed out to all exam candidates at the beginning of the exam.

Language of examination

You may submit your response in Norwegian, Swedish, Danish or English. If you would prefer to have the exam text in English, you may apply to the course administrators.

Grading scale

Grades are awarded on a pass/fail scale. Read more about the grading system.

Resit an examination

This course offers both postponed and resit of examination. Read more:

Special examination arrangements, use of sources, explanations and appeals

See more about examinations at UiO

Last updated from FS (Common Student System) Oct. 25, 2020 9:10:29 PM

Facts about this course


The course is last held spring 2020


Examination is last held spring 2022

Teaching language
Norwegian (English on request)