Characterize a toxic protein from a bacterium that infects salmon

We want to characterize a toxic protein from a bacterium that infects salmon. In collaboration with an Oslo-based company engaged in fish vaccines, we intend to clone, express, and purify the toxin. The toxin will then be tested for its enzymatic properties. Based on the disease manifestation, we assume that the toxin is actively degrading fish skin and fish bone. The project relies on methods in molecular biology and protein biochemistry, and includes elements of bioinformatics (sequence analysis, homology searches). An ideal candidate should have documented, hands-on experience in molecular cloning or protein purification (e.g. from relevant courses).


As some of the information on this project is "sensitive" as it may relate to patent applications, it is not possible to give much more detail here. If you are interested, please contact Dirk Linke directly.

Publisert 22. jan. 2019 15:03 - Sist endret 7. aug. 2019 10:55


Omfang (studiepoeng)