Jon Michael Gran

• Gran, Jon Michael & Stensrud, Mats Julius (2024). Avhengig sensurering. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 144(1), s. 1–3. doi: 10.4045/tidsskr.23.0685.
• Gran, Jon Michael & Stensrud, Mats Julius (2023). Konkurrerende hendelser. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(17). doi: 10.4045/tidsskr.23.0648.
• Hasting, Rachel Louise; Mehlum, Ingrid Sivesind; Undem, Karina; Robroek, Suzan J. W; Burdorf, Alex & Gran, Jon Michael [Vis alle 7 forfattere av denne artikkelen] (2023). The effects of a national, voluntary agreement for a more inclusive working life on work participation following long-term sickness absence: a Norwegian cohort study. Scandinavian Journal of Work, Environment and Health. ISSN 0355-3140. 49(7), s. 466–476. doi: 10.5271/sjweh.4112. Fulltekst i vitenarkiv Vis sammendrag

  Objectives This study aimed to estimate the average individual effect of the company-level Norwegian Agreement on a More Inclusive Working Life (IA Agreement) on individuals’ (i) sustained return to work after a sickness absence (SA) episode, and (ii) recurrent SA. Methods Using register data, 79 253 men and 94 914 women born in Norway 1967–1976 were followed for one year between 2005 and 2010 after returning to work from an SA episode (>16 days). Weighted Cox proportional hazard models analysed time to first exit from work by companies’ IA status (IA/non-IA). Weighted cumulative incidence differences between IA and non-IA groups with 95% bootstrapped confidence intervals (CI) were calculated for the competing events of full SA, graded (<100%) SA, unemployment/economic inactivity, education, disability pension, and death/emigration. Stabilised inverse probability of treatment weights balanced IA/non-IA groups according to nine covariates. Analyses were stratified by gender, and separately for two initial SA diagnoses (musculoskeletal and psychological). Results Both men [adjusted hazard ratio (HR) 0.96, 95% CI 0.93–0.99] and women (adjusted HR 0.97, 95% CI 0.94–0.99) in IA companies were less likely to exit work in the year following SA. Similar findings were seen among individuals with musculoskeletal diagnoses and women with psychological diagnoses. Men with psychological diagnoses were more likely to exit work. Recurrent full and graded SA were more likely, and unemployment/economic inactivity less likely, in IA companies. However, the estimated effects were small and the CI often included the null. Conclusions Individuals working in IA companies were more likely to remain in work. This was mainly due to reduced unemployment/economic inactivity, suggesting the IA Agreement may have influenced work participation through other means than reduced SA.

• Thorsen, Lene; Courneya, Kerry S.; Steene-Johannessen, Jostein; Gran, Jon Michael; Haugnes, Hege Sagstuen & Negaard, Helene Francisca Stigter [Vis alle 8 forfattere av denne artikkelen] (2023). Association of physical activity with overall mortality among long-term testicular cancer survivors: A longitudinal study. International Journal of Cancer. ISSN 0020-7136. 153(8), s. 1512–1519. doi: 10.1002/ijc.34625. Fulltekst i vitenarkiv Vis sammendrag

  Physical activity (PA) has been associated with reduced mortality among cancer survivors, but no study has focused on testicular cancer survivors (TCSs). We aimed to investigate the association of PA measured twice during survivorship with overall mortality in TCSs. TCSs treated during 1980 to 1994 participated in a nationwide longitudinal survey between 1998 to 2002 (S1: n = 1392) and 2007 to 2009 (S2: n = 1011). PA was self-reported by asking for the average hours per week of leisure-time PA in the past year. Responses were converted into metabolic equivalent task hours/week (MET-h/wk) and participants were categorized into: Inactives (0 MET-h/wk), Low-Actives (2-6 MET-h/wk), Actives (10-18 MET-h/wk) and High-Actives (20-48 MET-h/wk). Mortality from S1 and S2, respectively, was analyzed using the Kaplan-Meier estimator and Cox proportional hazards models until the End of Study (December 31, 2020). Mean age at S1 was 45 years (SD 10.2). Nineteen percent (n = 268) of TCSs died between S1 and EoS, with 138 dying after S2. Compared to Inactives at S1, the mortality risk among Actives was 51% lower (HR 0.49, 95% CI: 0.29-0.84) with no further mortality reduction among High-Actives. At S2, the mortality risk was at least 60% lower among the Actives, High-Actives and even the Low-Actives compared to the Inactives. Persistent Actives (≥10 MET-h/wk at S1 and S2) had a 51% lower mortality risk compared to Persistent Inactives (<10 MET-h/wk at S1 and S2; HR 0.49, 95% CI: 0.30-0.82). During long-term survivorship after TC treatment, regular and maintained PA were associated with an overall mortality risk reduction of at least 50%.

• Keogh, Ruth H.; Gran, Jon Michael; Seaman, Shaun R.; Davies, Gwyneth & Vansteelandt, Stijn (2023). Causal inference in survival analysis using longitudinal observational data: Sequential trials and marginal structural models. Statistics in Medicine. ISSN 0277-6715. 42(13), s. 2191–2225. doi: 10.1002/sim.9718. Fulltekst i vitenarkiv
• Methi, Fredrik; Gran, Jon Michael; Valberg, Morten; Kinge, Jonas Minet; Telle, Kjetil & Magnusson, Karin (2023). Third dose mRNA vaccination against SARS-CoV-2 reduces medical complaints seen in primary care: a matched cohort study. BMC Medicine. ISSN 1741-7015. 21, s. 1–15. doi: 10.1186/s12916-023-02870-2. Fulltekst i vitenarkiv Vis sammendrag

  Background SARS-CoV-2 mRNA vaccination has been associated with both side effects and a reduction in COVID-related complaints due to the decrease in COVID-19 incidence. We aimed to investigate if individuals who received three doses of SARS-CoV-2 mRNA vaccines had a lower incidence of (a) medical complaints and (b) COVID-19-related medical complaints, both as seen in primary care, when compared to individuals who received two doses. Methods We conducted a daily longitudinal exact one-to-one matching study based on a set of covariates. We obtained a matched sample of 315,650 individuals aged 18–70 years who received the 3rd dose at 20–30 weeks after the 2nd dose and an equally large control group who did not. Outcome variables were diagnostic codes as reported by general practitioners or emergency wards, both alone and in combination with diagnostic codes of confirmed COVID-19. For each outcome, we estimated cumulative incidence functions with hospitalization and death as competing events. Results We found that the number of medical complaints was lower in individuals aged 18–44 years who received three doses compared to those who received two doses. The differences in estimates per 100,000 vaccinated were as follows: fatigue 458 less (95% confidence interval: 355–539), musculoskeletal pain 171 less (48–292), cough 118 less (65–173), heart palpitations 57 less (22–98), shortness of breath 118 less (81–149), and brain fog 31 less (8–55). We also found a lower number of COVID-19-related medical complaints: per 100,000 individuals aged 18–44 years vaccinated with three doses, there were 102 (76–125) fewer individuals with fatigue, 32 (18–45) fewer with musculoskeletal pain, 30 (14–45) fewer with cough, and 36 (22–48) fewer with shortness of breath. There were no or fewer differences in heart palpitations (8 (1–16)) or brain fog (0 (− 1–8)). We observed similar results, though more uncertain, for individuals aged 45–70 years, both for medical complaints and for medical complaints that were COVID-19 related. Conclusions Our findings suggest that a 3rd dose of SARS-CoV-2 mRNA vaccine administered 20–30 weeks after the 2nd dose may reduce the incidence of medical complaints. It may also reduce the COVID-19-related burden on primary healthcare services.

• Bowe, Sophie; Mitlid-Mork, Birgitte; Gran, Jon Michael; Distante, Sonia; Redman, Christopher W.G. & Staff, Anne Cathrine [Vis alle 8 forfattere av denne artikkelen] (2022). Predelivery placenta-associated biomarkers and computerized intrapartum fetal heart rate patterns. AJOG Global Reports. 3(1). doi: 10.1016/j.xagr.2022.100149. Fulltekst i vitenarkiv Vis sammendrag

  Background Increasing syncytiotrophoblast stress in term and postdate placentas is reflected by increasing antiangiogenic dysregulation in the maternal circulation, with low “proangiogenic” placental growth factor concentrations and increased “antiangiogenic” soluble fms-like tyrosine kinase-1 concentrations. Imbalances in these placenta-associated proteins are associated with intrapartum fetal compromise and adverse pregnancy and delivery outcome. Cardiotocography is widely used to assess fetal well-being during labor, but it is insufficient on its own for predicting adverse neonatal outcome. Development of improved surveillance tools to detect intrapartum fetal stress are needed to prevent neonatal adverse outcome. Objective This study aimed to assess whether predelivery circulating maternal angiogenic protein concentrations are associated with intrapartum computerized fetal heart rate patterns, as calculated by the Oxford System for computerized intrapartum monitoring (OxSys) 1.7 prototype. We hypothesized that in pregnancies with low “proangiogenic” placental growth factor levels, increased “antiangiogenic” soluble fms-like tyrosine kinase-1 levels, and increased soluble fms-like tyrosine kinase-1–placental growth factor ratio, the OxSys 1.7 prototype will generate more automated alerts, indicating fetal compromise. Our secondary objective was to investigate the relationship between maternal circulating placenta-associated biomarkers and rates of automated alerts in pregnancies with and without adverse neonatal outcome. Study Design This was an observational prospective cohort study conducted at a single tertiary center from September 2016 to March 2020. Of 1107 singleton pregnancies (gestational week ≥37+0), 956 had available prelabor and predelivery placental growth factor and soluble fms-like tyrosine kinase-1 concentrations and intrapartum cardiotocography recordings. All neonatal and delivery outcomes were externally reviewed and categorized into 2 groups—the “complicated” group (n=32) and the “uncomplicated” group (n=924)—according to predefined adverse neonatal outcome. Eight different cardiotocography features were calculated by OxSys 1.7: baseline at start of cardiotocography, baseline at end of cardiotocography, short-term variation at start, short-term variation at end, nonreactive initial trace, and throughout the entire cardiotocography, maximum decelerative capacity, total number of prolonged decelerations, and OxSys 1.7 alert. OxSys 1.7 triggered an alert if the initial trace was nonreactive or if decelerative capacity and/or the number of prolonged decelerations exceeded a predefined threshold. Included women and attending clinicians were blinded to both biomarker and OxSys 1.7 results. Results Mean maternal placental growth factor concentration was lower in the group with OxSys 1.7 alert compared with the group without the alert (151 vs 169 pg/mL; P=.04). There was a weak negative correlation between predelivery high soluble fms-like tyrosine kinase-1 and low short-term variation start (rs=−0.068; 95% confidence interval, −0.131 to −0.004; P=.036), predelivery high soluble fms-like tyrosine kinase-1 and low short-term variation end (rs=−0.068; 95% confidence interval, −0.131 to −0.005; P=.036), and high soluble fms-like tyrosine kinase-1–placental growth factor ratio and low short-term variation end (rs=−0.071; 95% confidence interval, −0.134 to −0.008; P=.027). The rate of decelerative capacity alerts increased more rapidly as placental growth factor decreased in the “complicated” compared with the “uncomplicated” group (0% to 17% vs 4% to 8%). Conclusion More automated alerts indicative of fetal distress were generated by OxSys 1.7 in pregnancies with low maternal predelivery placental growth factor level, in line with likely increasing placental stress toward the end of the pregnancy. An antiangiogenic predelivery profile...

• Sundbakk, Lene Maria; Gran, Jon Michael; Wood, Mollie; Handal, Marte; Skurtveit, Svetlana Ondrasova & Nordeng, Hedvig Marie Egeland (2022). Association of Prenatal Exposure to Benzodiazepines and Z-Hypnotics With Risk of Attention-Deficit/Hyperactivity Disorder in Childhood. JAMA Network Open. ISSN 2574-3805. 5(12), s. 1–15. doi: 10.1001/jamanetworkopen.2022.46889. Fulltekst i vitenarkiv
• Hoff, Rune; Maltzahn, Niklas; Hasting, Rachel Louise; Merkus, Suzanne; Undem, Karina & Kristensen, Petter [Vis alle 8 forfattere av denne artikkelen] (2022). An initiative for a more inclusive working life and its effect on return-to-work after sickness absence: a multistate longitudinal cohort study. Occupational and Environmental Medicine. ISSN 1351-0711. 12(11). doi: 10.1136/bmjopen-2022-062558. Vis sammendrag

  Objectives To reduce sickness absence (SA) and increase work participation, the tripartite Agreement for a More Inclusive Working Life (IA) was established in Norway in 2001. IA companies have had access to several measures to prevent and reduce SA. Our aim in this paper was to estimate the average effect of having access to IA at the time of entering a first SA on later return-to-work (RTW) and on time spent in other work-related states. A secondary objective was to study how effects varied between women and men, and individuals with SA due to either musculoskeletal or psychological diagnoses. Design Population-based observational multistate longitudinal cohort study. Setting Individual characteristics and detailed longitudinal records of SA, work and education between 1997-2011 were obtained from population-wide registries. Participants Each individual born in Norway 1967–1976 who entered full-time SA during 2004–2011, with limited earlier SA, was included (n=187 930). Primary and secondary outcome measures Individual multistate histories containing dated periods of work, graded SA, full-time SA, non-employment and education. Methods Data were analysed in a multistate model with 500 days of follow-up. The effect of IA was assessed by estimating differences in state probabilities over time, adjusted for confounders, using inverse probability weighting. Results IA increased the probability of work after SA, with the largest difference between groups after 29 days (3.4 percentage points higher (95% CI 2.5 to 4.3)). Differences in 1-year expected length of stay were 8.4 additional days (4.9 to 11.9) in work, 7.6 (4.8 to 10.3) fewer days in full-time SA and 1.6 (-0.2 to 3.4) fewer days in non-employment. Similar trends were found within subgroups by sex, musculoskeletal and psychological diagnoses. The robustness of the findings was studied in sensitivity analyses. Conclusion Measures to prevent and reduce SA, as given through IA, were found to improve individuals’ RTW after entering SA.

• Lopez-Doriga Ruiz, Paz; Gunnes, Nina; Gran, Jon Michael; Karlstad, Øystein; Selmer, Randi Marie & Dahl, Jesper [Vis alle 15 forfattere av denne artikkelen] (2022). Short-term safety of COVID-19 mRNA vaccines with respect to all-cause mortality in the older population in Norway. Vaccine. ISSN 0264-410X. 41(2), s. 323–332. doi: 10.1016/j.vaccine.2022.10.085. Fulltekst i vitenarkiv
• Kvakkestad, Kristin Marie; Gran, Jon Michael & Halvorsen, Sigrun (2022). Short-and long-term survival after ST-elevation myocardial infarction treated with pharmacoinvasive versus primary percutaneous coronary intervention strategy: a prospective cohort study. BMJ Open. ISSN 2044-6055. 12(7). doi: 10.1136/bmjopen-2022-061590. Fulltekst i vitenarkiv Vis sammendrag

  Objective Compare survival in patients with ST-elevation myocardial infarction (STEMI) treated with a pharmacoinvasive (PI) or primary percutaneous coronary intervention (pPCI) strategy based on estimated time to PCI. Design Prospective observational cohort study. Consecutive STEMI patients were registered on admission to our PCI centre and classified in a PI or pPCI group, based on the reperfusion strategy chosen in the prehospital or local hospital location. Time and cause of death was provided by the Norwegian Cause of Death registry. Mortality at 30 days, Kaplan-Meier survival and incidence of cardiovascular (CV) death was estimated. Adjusted effect of PI versus pPCI strategy on survival was estimated using logistic and Cox regression and propensity score weighting. Setting Single-centre registry in Norway during 2005–2011, within a regional STEMI network allocating patients to a PI strategy if estimated time to PCI >120 min. Primary outcomes 30-day mortality and survival during follow-up. Secondary outcome Incidence of CV death during follow-up. Results 4061 STEMI patients <80 years were included, 527 (13%) treated with a PI strategy and 3534 (87%) with a pPCI strategy. Median symptom-to-needle time was 110 min (25–75th percentile 75–163) in the PI group vs symptom-to-balloon 230 min (149–435) in the pPCI group. 30-day mortality was 3.2% and 5.0% in the PI and pPCI groups (ORadjusted0.58 (95% CI 0.30 to 1.13)) and 8-year survival was 85.9% (95% CI 80.9% to 89.6%) and 79.3% (95% CI 76.9% to 81.6%), respectively (HRadjusted 0.72 (95% CI 0.53 to 0.99)). Unadjusted incidence of 8-year CV death was 7.0% (95% CI 4.4% to 10.4%) in the PI group vs 12.4% (95% CI 9.9% to 15.2%) in the pPCI group. Adjusted long-term CV death was also lower in the PI group. Conclusion STEMI patients treated with a PI strategy experienced better survival compared with a pPCI strategy, also when adjusting for baseline characteristics. This supports using a PI strategy for eligible STEMI patients when pPCI cannot be performed within 120 min.

• Undem, Karina; Leinonen, Taina; Kristensen, Petter; Merkus, Suzanne; Hasting, Rachel Louise & Gran, Jon Michael [Vis alle 7 forfattere av denne artikkelen] (2022). Gender Differences in Associations between Biomechanical and Psychosocial Work Exposures and Age of Withdrawal from Paid Employment among Older Workers. International Journal of Environmental Research and Public Health (IJERPH). ISSN 1661-7827. 19(17). doi: 10.3390/ijerph191710563. Fulltekst i vitenarkiv Vis sammendrag

  Background: Work exposures are known predictors of withdrawal from employment, but the associations between work exposures and withdrawal may vary with gender. This study evaluated gender differences in associations between biomechanical and psychosocial work exposures and age of withdrawal from paid employment among older workers in Norway. Methods: 77,558 men and 67,773 women (born 1949–1953) were followed from age 62 until withdrawal from paid employment or end of follow-up in 2016 (up to five years follow-up). Information about eight biomechanical and seven psychosocial exposures was obtained from a gender-specific job exposure matrix. Using Cox regression, the difference in mean estimated time until withdrawal between non-exposed and exposed was calculated for each gender and work exposure separately. Results: The largest gender difference was found for high psychological demands. Among men, the non-exposed withdrew earlier than the exposed (−3.66 months (95% CI: −4.04–−3.25 months)), and contrary among women (0.71 (0.28–1.10)), resulting in a gender difference of 4.37 (3.81–4.97) months. Gender differences were also found for monotonous work (4.12 (3.51–4.69) months), hands above shoulder height (2.41 (1.76–3.10) months), and high iso-strain (2.14 (1.38–2.95) months). Conclusions: There were observed gender differences in the associations between some biomechanical and psychosocial work exposures and mean age of withdrawal from paid employment among older workers. However, the results are likely affected by the selection of who remains in the workforce at age 62 and should be interpreted accordingly.

• Hasvik, Eivind Olay; Gran, Jon Michael; Haugen, Anne Julsrud & Grøvle, Lars (2022). Strategies to manage auxiliary pain medications in chronic pain trials: a topical review. European Journal of Clinical Pharmacology. ISSN 0031-6970. 78, s. 1377–1384. doi: 10.1007/s00228-022-03355-6. Fulltekst i vitenarkiv
• Hasting, Rachel Louise; Merkus, Suzanne; Hanvold, Therese Nordberg; Kristensen, Petter; Gran, Jon Michael & Mehlum, Ingrid Sivesind (2022). Impact of the Norwegian Agreement for a More Inclusive Working Life on diagnosis-specific sickness absence in young adults: a difference-in-difference analysis. BMC Public Health. ISSN 1471-2458. 22. doi: 10.1186/s12889-022-12636-9. Fulltekst i vitenarkiv Vis sammendrag

  Background The Norwegian Agreement for a More Inclusive Working Life (the IA Agreement) aims to reduce sickness absence (SA) and increase work participation. Potential impacts of the IA Agreement have not been thoroughly evaluated. The study aimed to estimate the impact of the IA Agreement on musculoskeletal and psychological SA prevalence and duration among young adult men and women, and to identify whether the impact was modified by economic activity or SA grade. Methods Data from national registries were combined for 372,199 individuals born in Norway 1967–1976. ICPC-2 codes identified musculoskeletal (L) and psychological (P) diagnoses. A difference-in-difference method compared prevalence and mean duration of first SA > 16 days between 2000 and 2005 separately for men and women working in IA companies relative to non-IA companies. Analyses were adjusted for mean company size and stratified by economic activity and SA grade (full/graded). Average marginal change was calculated with 95% confidence intervals (CI). Results The impacts of the IA Agreement on SA prevalence were mixed as the direction and size of marginal changes varied according to diagnosis, gender, and economic activity. However, there was a general tendency towards reduced mean SA duration for both diagnosis groups, and in particular men with musculoskeletal SA (− 16.6 days, 95% CI -25.3, − 7.9). Individuals with full SA in IA companies had greater reductions in mean SA duration. Only the wholesale and retail economic activity indicated a beneficial contribution of the IA Agreement for both SA prevalence and duration, in both diagnoses and genders. Conclusions Potential impacts of the IA Agreement on SA in young men and women varied according to diagnosis and economic activity. However, results indicated that the IA Agreement could reduce SA duration. Further research should identify reasons for gender and economic activity differences.

• Keogh, Ruth H.; Seaman, Shaun; Gran, Jon Michael & Vansteelandt, Stijn (2021). Simulating longitudinal data from marginal structural models using the additive hazard model. Biometrical Journal. ISSN 0323-3847. 63(7), s. 1526–1541. doi: 10.1002/bimj.202000040. Fulltekst i vitenarkiv
• Torp, Henrik Andreas; Skurtveit, Svetlana Ondrasova; Skaga, Nils Oddvar; Gustavsen, Ingebjørg G.; Gran, Jon Michael & Rosseland, Leiv Arne (2021). Pre-injury dispensing of psychoactive prescription drugs in a ten years trauma population: a retrospective registry analysis. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 29. doi: 10.1186/s13049-021-00939-6. Fulltekst i vitenarkiv
• Maltzahn, Niklas; Hoff, Rune; Aalen, Odd O.; Mehlum, Ingrid S.; Putter, Hein & Gran, Jon Michael (2021). A hybrid landmark Aalen-Johansen estimator for transition probabilities in partially non-Markov multi-state models. Lifetime Data Analysis. ISSN 1380-7870. 27, s. 737–760. doi: 10.1007/s10985-021-09534-4. Fulltekst i vitenarkiv Vis sammendrag

  Multi-state models are increasingly being used to model complex epidemiological and clinical outcomes over time. It is common to assume that the models are Markov, but the assumption can often be unrealistic. The Markov assumption is seldomly checked and violations can lead to biased estimation of many parameters of interest. This is a well known problem for the standard Aalen-Johansen estimator of transition probabilities and several alternative estimators, not relying on the Markov assumption, have been suggested. A particularly simple approach known as landmarking have resulted in the Landmark-Aalen-Johansen estimator. Since landmarking is a stratification method a disadvantage of landmarking is data reduction, leading to a loss of power. This is problematic for “less traveled” transitions, and undesirable when such transitions indeed exhibit Markov behaviour. Introducing the concept of partially non-Markov multi-state models, we suggest a hybrid landmark Aalen-Johansen estimator for transition probabilities. We also show how non-Markov transitions can be identified using a testing procedure. The proposed estimator is a compromise between regular Aalen-Johansen and landmark estimation, using transition specific landmarking, and can drastically improve statistical power. We show that the proposed estimator is consistent, but that the traditional variance estimator can underestimate the variance of both the hybrid and landmark estimator. Bootstrapping is therefore recommended. The methods are compared in a simulation study and in a real data application using registry data to model individual transitions for a birth cohort of 184 951 Norwegian men between states of sick leave, disability, education, work and unemployment.

• Stenehjem, Jo Steinson; Røise, Olav; Nordseth, Trond; Clausen, Thomas; Natvig, Bård & Skurtveit, Svetlana Ondrasova [Vis alle 10 forfattere av denne artikkelen] (2021). Injury Prevention and long-term Outcomes following Trauma - The IPOT project: a protocol for prospective nationwide registry-based studies in Norway. BMJ Open. ISSN 2044-6055. 11(5). doi: 10.1136/bmjopen-2020-046954. Fulltekst i vitenarkiv
• Bowe, Sophie; Mitlid-Mork, Birgitte; Georgieva, Antoniya; Gran, Jon M.; Redman, Christopher W.G. & Staff, Anne Cathrine [Vis alle 7 forfattere av denne artikkelen] (2021). The association between placenta-associated circulating biomarkers and composite adverse delivery outcome of a likely placental cause in healthy post-date pregnancies. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 100(10), s. 1893–1901. doi: 10.1111/aogs.14223. Fulltekst i vitenarkiv
• Juhl, Claus Bogh; Holst, René; Mundbjerg, Lene Hymøller; Stolberg, Charlotte; Gran, Jon Michael & Thomsen, Gert Frank (2021). Effect of bariatric surgery on employment status -a 7 years controlled nationwide registry study. BMJ Open. ISSN 2044-6055. 11(6). doi: 10.1136/bmjopen-2020-042845. Fulltekst i vitenarkiv
• Øjlert, Åsa Kristina; Nebdal, Daniel J.H.; Lund-Iversen, Marius; Ellefsen, Renée Åstrøm; Brustugun, Odd Terje & Gran, Jon Michael [Vis alle 8 forfattere av denne artikkelen] (2020). Immune checkpoint blockade in the treatment of advanced non-small cell lung cancer–predictors of response and impact of previous radiotherapy. Acta Oncologica. ISSN 0284-186X. s. 1–9. doi: 10.1080/0284186X.2020.1854851. Fulltekst i vitenarkiv
• Mitlid-Mork, Birgitte; Bowe, Sophie; Gran, Jon Michael; Bolstad, Nils; Berg, Jens Petter & Redman, Christopher W.G. [Vis alle 8 forfattere av denne artikkelen] (2020). Maternal placental growth factor and soluble fms-like tyrosine kinase-1 reference ranges in post-term pregnancies: A prospective observational study. PLOS ONE. ISSN 1932-6203. 15:e0240473(10), s. 1–14. doi: 10.1371/journal.pone.0240473. Fulltekst i vitenarkiv
• Gunnes, Nina; Gjessing, Håkon K.; Bakken, Inger Johanne Landsjøåsen; Ghaderi, Sara; Gran, Jon Michael & Hungnes, Olav [Vis alle 13 forfattere av denne artikkelen] (2020). Seasonal and pandemic influenza during pregnancy and risk of fetal death: A Norwegian registry‑based cohort study. European Journal of Epidemiology (EJE). ISSN 0393-2990. 35, s. 371–379. doi: 10.1007/s10654-020-00600-z. Fulltekst i vitenarkiv
• Gottschalk, Marthe Sørli; Eskild, Anne; Hofvind, Solveig; Gran, Jon Michael & Bjelland, Elisabeth Krefting (2020). Temporal trends in age at menarche and age at menopause: a population study of 312 656 women in Norway. Human Reproduction. ISSN 0268-1161. 35(2), s. 464–471. doi: 10.1093/humrep/dez288. Fulltekst i vitenarkiv
• Bjelland, Elisabeth Krefting; Gran, Jon Michael; Hofvind, Solveig & Eskild, Anne (2020). The association of birthweight with age at natural menopause: a population study of women in Norway. International Journal of Epidemiology. ISSN 0300-5771. 49(2), s. 528–536. doi: 10.1093/ije/dyz207. Fulltekst i vitenarkiv
• Kvakkestad, Kristin Marie; Gran, Jon Michael; Eritsland, Jan; Hansen, Charlotte Holst; Fossum, Eigil & Andersen, Geir Øystein [Vis alle 7 forfattere av denne artikkelen] (2019). Long-term survival after invasive or conservative strategy in elderly patients with non-ST-elevation myocardial infarction: A prospective cohort study. Cardiology. ISSN 0008-6312. s. 1–11. doi: 10.1159/000503442. Fulltekst i vitenarkiv
• Djordjilovic, Vera; Page, Christian Magnus; Gran, Jon Michael; Nøst, Therese Haugdahl; Sandanger, Torkjel M & Veierød, Marit Bragelien [Vis alle 7 forfattere av denne artikkelen] (2019). Global test for high-dimensional mediation: Testing groups of potential mediators. Statistics in Medicine. ISSN 0277-6715. 38(18), s. 3346–3360. doi: 10.1002/sim.8199. Fulltekst i vitenarkiv
• Sundbakk, Lene Maria; Wood, Mollie; Gran, Jon Michael & Nordeng, Hedvig Marie Egeland (2019). Impact of prenatal exposure to benzodiazepines and z-hypnotics on behavioral problems at 5 years of age: A study from the Norwegian Mother and Child Cohort Study. PLOS ONE. ISSN 1932-6203. 14(6). doi: 10.1371/journal.pone.0217830. Fulltekst i vitenarkiv
• Ofstad, Anne Pernille; Sommer, Christine; Birkeland, Kåre I.; Bjørgaas, Marit Ragnhild Rokne; Gran, Jon Michael & Gulseth, Hanne Løvdal [Vis alle 7 forfattere av denne artikkelen] (2019). Comparison of the associations between non-traditional and traditional indices of adiposity and cardiovascular mortality: an observational study of one million person-years of follow-up. International Journal of Obesity. ISSN 0307-0565. 43(5), s. 1082–1092. doi: 10.1038/s41366-019-0353-9. Fulltekst i vitenarkiv
• Hoff, Rune; Putter, Hein; Mehlum, Ingrid Sivesind & Gran, Jon Michael (2019). Landmark estimation of transition probabilities in non-Markov multi-state models with covariates. Lifetime Data Analysis. ISSN 1380-7870. 25(4), s. 660–680. doi: 10.1007/s10985-019-09474-0. Fulltekst i vitenarkiv Vis sammendrag

  In non-Markov multi-state models, the traditional Aalen–Johansen (AJ) estimator for state transition probabilities is generally not valid. An alternative, suggested by Putter and Spitioni, is to analyse a subsample of the full data, consisting of the individuals present in a specific state at a given landmark time-point. The AJ estimator of occupation probabilities is then applied to the landmark subsample. Exploiting the result by Datta and Satten, that the AJ estimator is consistent for state occupation probabilities even in non-Markov models given that censoring is independent of state occupancy and times of transition between states, the landmark Aalen–Johansen (LMAJ) estimator provides consistent estimates of transition probabilities. So far, this approach has only been studied for non-parametric estimation without covariates. In this paper, we show how semi-parametric regression models and inverse probability weights can be used in combination with the LMAJ estimator to perform covariate adjusted analyses. The methods are illustrated by a simulation study and an application to population-wide registry data on work, education and health-related absence in Norway. Results using the traditional AJ estimator and the LMAJ estimator are compared, and show large differences in estimated transition probabilities for highly non-Markov multi-state models.

• Dieset, Ingrid; Mørch, Ragni Helene; Hope, Sigrun; Hoseth, Eva Zsuzsanna; Reponen, Elina Johanna & Gran, Jon Michael [Vis alle 16 forfattere av denne artikkelen] (2018). An association between YKL-40 and type 2 diabetes in psychotic disorders. Acta Psychiatrica Scandinavica. ISSN 0001-690X. 139, s. 37–45. doi: 10.1111/acps.12971. Fulltekst i vitenarkiv
• Svendsen, Karianne; Telle-Hansen, Vibeke; Telle-Hansen, Vibeke; Mørch-Reiersen, Lisa T.; Mørch-Reiersen, Lisa Therese & Garstad, Kjersti W. [Vis alle 14 forfattere av denne artikkelen] (2018). A randomized controlled trial in Norwegian pharmacies on effects of risk alert and advice in people with elevated cardiovascular risk. Preventive Medicine Reports. ISSN 2211-3355. 12, s. 79–86. doi: 10.1016/j.pmedr.2018.08.004. Fulltekst i vitenarkiv
• Shetelig, Christian; Limalanathan, Shanmuganathan; HOFFMANN, PAVEL; Seljeflot, Ingebjørg; Gran, Jon Michael & Eritsland, Jan [Vis alle 7 forfattere av denne artikkelen] (2018). Association of IL-8 With Infarct Size and Clinical Outcomes in Patients With STEMI. Journal of the American College of Cardiology. ISSN 0735-1097. 72(2), s. 187–198. doi: 10.1016/j.jacc.2018.04.053.
• Hoff, Rune; Corbett, Karina; Mehlum, Ingrid Sivesind; Mohn, Ferdinand A; Kristensen, Petter & Hanvold, Therese Nordberg [Vis alle 7 forfattere av denne artikkelen] (2018). The impact of completing upper secondary education - a multi-state model for work, education and health in young men. BMC Public Health. ISSN 1471-2458. 18. doi: 10.1186/s12889-018-5420-y. Fulltekst i vitenarkiv Vis sammendrag

  Background: Completing upper secondary education is associated with higher work participation and less health-related absence from work. Although these outcomes are closely interrelated, most studies focus on single outcomes, using cross-sectional designs or short follow-up periods. As such, there is limited knowledge of the long-term outcomes, and how paths for completers and non-completers unfold over time. In this paper, we use multi-state models for time-to-event data to assess the long-term effects of completing upper secondary education on employment, tertiary education, sick leave, and disability pension over twelve and a half years for young men. Methods: Baseline covariates and twelve and a half years of follow-up data on employment, tertiary education, sick leave and disability pension were obtained from national registries for all males born in Norway between 1971 and 1976 (n =184951). The effects of completing upper secondary education (by age 23) were analysed in a multi-state framework, adjusting for both individual and family level confounders. All analyses were done separately for general studies and vocational tracks. Results: Completers do better on a range of outcomes compared to non-completers, for both fields of upper secondary education, but effects of completion change over time. The largest changes are for tertiary education and work, with the probability of work increasing reciprocally to the probability of education. Vocational students are quicker to transfer to the labour market, but tend to have more unemployment, sick leave and disability, and the absolute effects of completion on these outcomes are largest for vocational tracks. However, the relative effects of completion are larger for general studies. Conclusion: Completing upper secondary education increases long-term work participation and lowers health-related absence for young men, but effects diminish over time. Studies that have used shorter follow-up periods could be overstating the negative effects of dropout on labour market participation. Multi-state models are well suited to analyse data on work, education and health-related absence, and can be useful in understanding the dynamic aspects of these outcomes.

• Iuliano, A Danielle; Roguski, Katherine M; Chang, Howard H; Muscatello, David J; Palekar, Rakhee & Tempia, Stefano [Vis alle 25 forfattere av denne artikkelen] (2018). Estimates of global seasonal influenza-associated respiratory mortality: a modelling study. The Lancet. ISSN 0140-6736. 391(10127), s. 1285–1300. doi: 10.1016/S0140-6736(17)33293-2.
• Aalen, Odd O.; Gran, Jon Michael; Røysland, Kjetil; Stensrud, Mats Julius & Strohmaier, Susanne (2018). Feedback and Mediation in Causal Inference Illustrated by Stochastic Process Models. Scandinavian Journal of Statistics. ISSN 0303-6898. 45(1), s. 62–86. doi: 10.1111/sjos.12286.
• Gran, Jon Michael; Hoff, Rune; Røysland, Kjetil; Ledergerber, Bruno; Young, James & Aalen, Odd O. (2017). Estimating the treatment effect on the treated under time-dependent confounding in an application to the Swiss HIV Cohort Study. The Journal of the Royal Statistical Society, Series C (Applied Statistics). ISSN 0035-9254. 67(1), s. 103–125. doi: 10.1111/rssc.12221. Fulltekst i vitenarkiv
• Belay, Denekew Bitew; Kifle, Yehenew Getachew; Goshu, Ayele Taye; Gran, Jon Michael; Yewhalaw, Delenasaw & Duchateau, Luc [Vis alle 7 forfattere av denne artikkelen] (2017). Joint Bayesian modeling of time to malaria and mosquito abundance in Ethiopia. BMC Infectious Diseases. ISSN 1471-2334. 17(1). doi: 10.1186/s12879-017-2496-4. Fulltekst i vitenarkiv
• Astrup, Guro Lindviksmoen; Rustøen, Tone; Hofsø, Kristin; Gran, Jon Michael & Bjordal, Kristin (2017). Symptom burden and patient characteristics: Association with quality of life in patients with head and neck cancer undergoing radiotherapy. Head and Neck. ISSN 1043-3074. 39(10), s. 2114–2126. doi: 10.1002/hed.24875.
• Shetelig, Christian; Shanmuganathan, Limalanathan; Eritsland, Jan; HOFFMANN, PAVEL; Seljeflot, Ingebjørg & Gran, Jon Michael [Vis alle 9 forfattere av denne artikkelen] (2017). Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function. PLOS ONE. ISSN 1932-6203. 12:e0173034(3), s. 1–14. doi: 10.1371/journal.pone.0173034. Fulltekst i vitenarkiv
• Prague, Mélanie; Commenges, Daniel; Gran, Jon Michael; Ledergerber, Bruno; Young, Jim & Furrer, Hansjakob [Vis alle 7 forfattere av denne artikkelen] (2017). Dynamic models for estimating the effect of HAART on CD4 in observational studies: Application to the Aquitaine Cohort and the Swiss HIV Cohort Study. Biometrics. ISSN 0006-341X. 73(1), s. 294–304. doi: 10.1111/biom.12564.
• Torvik, Kristin; Narverud, Ingunn; Ottestad, Inger; Svilaas, Arne B; Gran, Jon Michael & Retterstøl, Kjetil [Vis alle 11 forfattere av denne artikkelen] (2016). Dietary counseling is associated with an improved lipid profile in children with familial hypercholesterolemia. Atherosclerosis. ISSN 0021-9150. 252, s. 21–27. doi: 10.1016/j.atherosclerosis.2016.07.913.
• Aalen, Odd O.; Røysland, Kjetil; Gran, Jon Michael; Kouyos, Roger & Lange, Theis (2016). Can we believe the DAGs? A comment on the relationship between causal DAGs and mechanisms. Statistical Methods in Medical Research. ISSN 0962-2802. 25(5), s. 2294–2314. doi: 10.1177/0962280213520436.
• Narverud, Ingunn; van Lennep, Jeanine Roeters; Christensen, Jacob Juel; Versmissen, Jorie; Gran, Jon Michael & Iversen, Per Ole [Vis alle 15 forfattere av denne artikkelen] (2015). Maternal inheritance does not predict cholesterol levels in children with familial hypercholesterolemia. Atherosclerosis. ISSN 0021-9150. 243(1), s. 155–160. doi: 10.1016/j.atherosclerosis.2015.09.014.
• Gran, Jon Michael; Lie, Stein Atle; Øyeflaten, Irene Larsen; Borgan, Ørnulf & Aalen, Odd O. (2015). Causal inference in multi-state models-sickness absence and work for 1145 participants after work rehabilitation. BMC Public Health. ISSN 1471-2458. 15:1082. doi: 10.1186/s12889-015-2408-8. Fulltekst i vitenarkiv
• Corbett, Karina; Gran, Jon Michael; Kristensen, Petter & Mehlum, Ingrid Sivesind (2015). Adult social position and sick leave: the mediating effect of physical workload. Scandinavian Journal of Work, Environment and Health. ISSN 0355-3140. 41(6), s. 542–553. doi: 10.5271/sjweh.3525. Vis sammendrag

  Objective: This study aimed to quantify how much of the adult social gradient in sick leave can be attributed to the mediating role of physical workload while accounting for the role of childhood and adolescent social position and neuroticism. Methods: Our sample consisted of 2099 women and 1229 men from a Norwegian birth cohort study (born 1967–1976) who participated in the Nord-Trøndelag Health Study (2006–2008) (HUNT3). Data on sick leave (defined as >16 calendar days; 2006–2009) and social position during childhood, adolescence, and adulthood were obtained from national registers. Study outcome was time-to-first sick leave spell. Physical workload and neuroticism were self-reported in HUNT3. Mediating effects through physical workload were estimated using a method based on the additive hazards survival model. Results: A hypothetical change from highest to lowest group in adult social position was, for women, associated with 51.6 [95% confidence interval (95% CI) 24.7–78.5] additional spells per 100 000 person-days at risk, in a model adjusted for childhood and adolescent social position and neuroticism. The corresponding rate increase for men was 41.1 (95% CI 21.4–60.8). Of these additional spells, the proportion mediated through physical workload was 24% (95% CI 10–49) and 30% (95% CI 10–63) for women and men, respectively. Conclusions: The effect of adult social position on sick leave was partly mediated through physical workload, even while accounting for earlier life course factors. Our findings provide support that interventions aimed at reducing physical workload among those with lower adult social position could reduce sick leave risk.

• Hoff, Rune; Gran, Jon Michael & Daniel, Farewell (2014). Farewell’s Linear Increments Model for Missing Data: The FLIM Package. The R Journal. ISSN 2073-4859. 6(2), s. 137–150. doi: 10.32614/rj-2014-030.
• Skjeldestad, Finn Egil; Bjørnholt, Jørgen; Gran, Jon Michael & Eriksen, Hanne-Merete (2014). The effect of antibiotic prophylaxis guidelines on surgical-site infections associated with cesarean delivery. International Journal of Gynecology & Obstetrics. ISSN 0020-7292. 128(2), s. 126–130. doi: 10.1016/j.ijgo.2014.08.018.
• Røislien, Jo; Clausen, Thomas; Gran, Jon Michael & Bukten, Anne (2014). Accounting for individual differences and timing of events: Estimating the effect of treatment on criminal convictions in heroin users. BMC Medical Research Methodology. ISSN 1471-2288. 14(68). doi: 10.1186/1471-2288-14-68.
• Gran, Jon Michael; Kacelnik, Oliver; Grjibovski, Andrej; Aavitsland, Preben & Iversen, Bjørn Gunnar (2013). Counting pandemic deaths: comparing reported numbers of death from influenza A(H1N1)pdm09 with estimated excess mortality. Influenza and Other Respiratory Viruses. ISSN 1750-2640. 7(6), s. 1370–1379. doi: 10.1111/irv.12125. Fulltekst i vitenarkiv
• Aalen, Odd O.; Røysland, Kjetil; Gran, Jon Michael & Ledergerber, Bruno (2012). Causality, mediation and time: a dynamic viewpoint. Journal of the Royal Statistical Society: Series A (Statistics in Society). ISSN 0964-1998. 175(4), s. 831–861. doi: 10.1111/j.1467-985X.2011.01030.x.
• De Blasio, Birgitte Freiesleben; Xue, Yiting; Iversen, Bjørn Gunnar & Gran, Jon Michael (2012). Estimating influenza-related sick leave in Norway: Was work absenteeism higher during the 2009 A(H1N1) pandemic compared to seasonal epidemics? Eurosurveillance. ISSN 1025-496X. 17(33), s. 15–25.
• Røysland, Kjetil; Gran, Jon Michael; Ledergerber, Bruno; von Wyl, Viktor; Young, James A. & Aalen, Odd O. (2011). Analyzing direct and indirect effects of treatment using dynamic path analysis applied to data from the Swiss HIV Cohort Study. Statistics in Medicine. ISSN 0277-6715. 30(24), s. 2947–2958. doi: 10.1002/sim.4324.
• Bentsen, Håvard; Solberg, Dag Kristen; Refsum, Helge; Gran, Jon Michael; Bøhmer, Thomas & Torjesen, Peter A [Vis alle 8 forfattere av denne artikkelen] (2011). Bimodal Distribution of Polyunsaturated Fatty Acids in Schizophrenia Suggests Two Endophenotypes of the Disorder. Biological Psychiatry. ISSN 0006-3223. 70(1), s. 97–105. doi: 10.1016/j.biopsych.2011.02.011.
• Reikvam, Dag Henrik; Perminow, Gøri Margrete; Lyckander, Lars Gustav; Gran, Jon Michael; Brandtzæg, Per & Vatn, Morten [Vis alle 7 forfattere av denne artikkelen] (2011). Increase of regulatory T cells in ileal mucosa of untreated pediatric Crohn's disease patients. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 46(5), s. 550–560. doi: 10.3109/00365521.2011.551887.
• Carlsen, Monica Hauger; Karlsen, Anette; Lillegaard, Inger Therese L.; Gran, Jon Michael; Drevon, Christian A & Blomhoff, Rune [Vis alle 7 forfattere av denne artikkelen] (2011). Relative validity of fruit and vegetable intake estimated from an FFQ, using carotenoid and flavonoid biomarkers and the method of triads. British Journal of Nutrition. ISSN 0007-1145. 105(10), s. 1530–1538. doi: 10.1017/S0007114510005246.
• Gran, Jon Michael; Iversen, Bjørn Gunnar; Hungnes, Olav & Aalen, Odd O. (2010). Estimating influenza-related excess mortality and reproduction numbers for seasonal influenza in Norway, 1975-2004. Epidemiology and Infection. ISSN 0950-2688. 138(11), s. 1559–1568. doi: 10.1017/S0950268810000671.
• Gran, Jon Michael; Røysland, Kjetil; Wolbers, Marcel; Didelez, Vanessa; Sterne, Jonathan AC & Ledergerber, Bruno [Vis alle 9 forfattere av denne artikkelen] (2010). A sequential Cox approach for estimating the causal effect of treatment in the presence of time-dependent confounding applied to data from the Swiss HIV Cohort Study. Statistics in Medicine. ISSN 0277-6715. 29(26), s. 2757–2768. doi: 10.1002/sim.4048.
• Haugaa, Kristina Hermann; Edvardsen, Thor; Leren, Trond P.; Gran, Jon Michael; Smiseth, Otto A. & Amlie, Jan Peder (2009). Left ventricular mechanical dispersion by tissue Doppler imaging: a novel approach for identifying high-risk individuals with long QT syndrome. European Heart Journal. ISSN 0195-668X. 30(3), s. 330–337. doi: 10.1093/eurheartj/ehn466.
• Gran, JM; Wasmuth, L; Amundsen, EJ; Lindqvist, Bo Henry & Aalen, OO (2008). Growth rates in epidemic models: Application to a model for HIV/AIDS progression. Statistics in Medicine. ISSN 0277-6715. 27, s. 4819–4836. doi: 10.1002/sim.3219. Vis sammendrag

  The most common quantity used to describe the growth of an epidemic when modelling infectious diseases is the basic reproduction number R0. While R0 is most appropriate for epidemics with short-lasting infections, long-lasting infections such as HIV/AIDS may call for the use of growth rates with other properties. For a group of multi-state compartment models we define both R0, the actual reproduction number Ra(t), and the intrinsic growth rate r .We study the relationship between these different reproduction numbers and growth rates and take a brief look at how they could be estimated from actual observed data. The work is illustrated by a model for HIV/AIDS progression among homosexual men in England and Wales. We conclude that other measures of growth, in addition to R0, give important supplementary information.

• Haugaa, Kristina Hermann; Edvardsen, Thor; Leren, TP; Gran, Jon Michael; Smiseth, Otto A. & Amlie, Jan Peder (2008). Left ventricular mechanical dispersion by tissue Doppler imaging: a novel approach for identifying high-risk individuals with long-QT syndrome. European Heart Journal. ISSN 0195-668X.

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• Danielsen, Anders Skyrud; Lim, Cherry; Yoon, Chang-Ho; Gran, Jon Michael; Kacelnik, Oliver & Eyre, David W. [Vis alle 7 forfattere av denne artikkelen] (2024). Excess mortality due to AMR in bacteraemias among cancer patients in Oxford and Oslo, 2008-2018.
• Valberg, Morten; Gran, Jon Michael; Rueegg, Corina Silvia & Leblanc, Marissa Erin (2022). Letter to the editor regarding “Covid-19 transmission in fitness centers in Norway - a randomized trial”. BMC Public Health. ISSN 1471-2458. 22(1). doi: 10.1186/s12889-022-14800-7.
• Rasmussen, Anders; Stenehjem, Jo Steinson; Røise, Olav; Gran, Jon Michael; Kristiansen, Thomas & Uleberg, Oddvar [Vis alle 8 forfattere av denne artikkelen] (2022). Standardised mortality rates for non-traumatic deaths among survivors of trauma in Norway (2015-2018).
• Gran, Jon Michael & Stensrud, Mats Julius (2022). Ulike typer interferens i randomiserte studier. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 142(9). doi: 10.4045/tidsskr.22.0059.
• Uleberg, Oddvar; Kristiansen, Thomas; Nordseth, Trond; Stenehjem, Jo S.; Gran, Jon Michael & Clausen, Thomas [Vis alle 8 forfattere av denne artikkelen] (2022). Skader etter vold og ulykker - den glemte pandemi? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 142(8), s. 678–679. doi: 10.4045/tidsskr.22.0261.
• Uleberg, Oddvar; Stenehjem, Jo S.; Nordseth, Trond; Clausen, Thomas; Natvig, Bård & Skurtveit, Svetlana Ondrasova [Vis alle 12 forfattere av denne artikkelen] (2022). The injury prevention and outcomes following trauma (IPOT) project: is a nationwide registry-based study in Norway feasible?
• Grødeland, Gunnveig; Sørvoll, Ingvild Hausberg; Befring, Anne Kjersti; Gran, Jon Michael; Krokstad, Steinar & Vorland, lars (2021). Vent på vaksinen du får tilbudt i det nasjonale vaksineprogrammet. VG : Verdens gang. ISSN 0805-5203.
• Befring, Anne Kjersti; Sørvoll, Ingvild Hausberg; Grødeland, Gunnveig; Krokstad, Steinar; Gran, Jon Michael & Pettersen, Frank O. (2021). Tåler neppe at friske dør. Dagbladet. ISSN 0805-3766.
• Stenehjem, Jo S.; Røise, Olav; Nordseth, Trond; Clausen, Thomas; Natvig, Bård & Skurtveit, Svetlana Ondrasova [Vis alle 12 forfattere av denne artikkelen] (2021). Injury Prevention and long-term Outcomes following Trauma - the IPOT project: a protocol for prospective nationwide registry-based studies in Norway.
• Rosseland, Leiv Arne; Stenehjem, Jo S.; Nordseth, Trond; Clausen, Thomas; Natvig, Bård & Skurtveit, Svetlana Ondrasova [Vis alle 12 forfattere av denne artikkelen] (2021). The Injury Prevention and Outcomes following Trauma project: a prospective nationwide registry-based study in Norway.
• Gran, Jon Michael & Stensrud, Mats Julius (2021). Målforsøk. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 5. doi: 10.4045/tidsskr.20.0839.
• Gottschalk, Marthe Sørli; Eskild, Anne; Hofvind, Solveig; Gran, Jon Michael & Bjelland, Elisabeth Krefting (2020). Reply: Menarche age, menopausal age and cumulative exposure to endogenous estrogens. Human Reproduction. ISSN 0268-1161. doi: 10.1093/humrep/deaa276.
• Stensrud, Mats Julius & Gran, Jon Michael (2020). Randomisering under en pandemi. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 140(10). doi: 10.4045/tidsskr.20.0439.
• Gottschalk, Marthe Sørli; Eskild, Anne; Hofvind, Solveig; Gran, Jon Michael & Bjelland, Elisabeth Krefting (2019). Temporal trends in age at menarche and age at menopause: a population study of 312 656 women in Norway.
• Bjelland, Elisabeth Krefting; Gran, Jon Michael; Hofvind, Solveig & Eskild, Anne (2019). The association of birthweight with age at natural menopause. A population study of women in Norway.
• Gottschalk, Marthe Sørli; Eskild, Anne; Hofvind, Solveig; Gran, Jon Michael & Bjelland, Elisabeth Krefting (2019). Temporal trends in age at menarche and age at menopause: a population study of 312 656 women in Norway. Norsk Epidemiologi, Supplement. ISSN 0803-4206. 28, s. 77–77.
• Gottschalk, Marthe Sørli; Eskild, Anne; Hofvind, Solveig; Gran, Jon Michael & Bjelland, Elisabeth Krefting (2019). Temporal trends in age at menarche and age at menopause: a population study of 312 656 women in Norway.
• Bjelland, Elisabeth Krefting; Gran, Jon Michael; Hofvind, Solveig & Eskild, Anne (2019). The association of birthweight with age at natural menopause. A population study of women in Norway. Norsk Epidemiologi, Supplement. ISSN 0803-4206. 28, s. 78–78.
• Bjelland, Elisabeth Krefting; Gran, Jon Michael; Hofvind, Solveig & Eskild, Anne (2019). The association of birthweight with age at natural menopause. A population study of women in Norway.
• Gran, Jon Michael & Aalen, Odd O. (2019). Letter to the Editor: Comparison of statistical approaches dealing with time-dependent confounding in drug effectiveness studies (SMMR, Vol. 27, Issue 6, 2018). Statistical Methods in Medical Research. ISSN 0962-2802. 28(1), s. 321–322. doi: 10.1177/0962280218811177.
• Sundbakk, Lene Maria; Wood, Mollie; Gran, Jon Michael & Nordeng, Hedvig Marie Egeland (2018). Does prenatal exposure to benzodiazepines or z-hypnotics increase the risk of behavioral problems at 5 years? .
• Sundbakk, Lene Maria; Nordeng, Hedvig Marie Egeland; Wood, Mollie & Gran, Jon Michael (2017). Prenatal exposure to benzodiazepines or z-hypnotics and behavioral problems at 5 years of age: A study from the Norwegian Mother and Child cohort study.
• Narverud, Ingunn; Bogsrud, Martin Prøven; Roeters van Lennep, Jeanine; Christensen, Jacob J.; Gran, Jon Michael & Galema-Boers, Annette [Vis alle 10 forfattere av denne artikkelen] (2017). MATERNAL CHOLESTEROL LEVELS MAY PREDICT LDL CHOLESTEROL LEVELS IN CHILDREN WITH FAMILIAL HYPERCHOLESTEROLEMIA.
• Narverud, Ingunn; Bogsrud, Martin Prøven; Roeters van Lennep, Jeanine; Christensen, Jacob J.; Gran, Jon Michael & Galema-Boers, Annette [Vis alle 10 forfattere av denne artikkelen] (2017). MATERNAL CHOLESTEROL LEVELS MAY PREDICT LDL CHOLESTEROL LEVELS IN CHILDREN WITH FAMILIAL HYPERCHOLESTEROLEMIA.
• Narverud, Ingunn; Bogsrud, Martin Prøven; Roeters van Lennep, Jeanine; Christensen, Jacob J.; Gran, Jon Michael & Galema-Boers, Annette [Vis alle 10 forfattere av denne artikkelen] (2017). MATERNAL CHOLESTEROL LEVELS MAY PREDICT LDL CHOLESTEROL LEVELS IN CHILDREN WITH FAMILIAL HYPERCHOLESTEROLEMIA.
• Svendsen, Karianne; Retterstøl, Kjetil; Telle-Hansen, Vibeke; Jacobs, David R. Jr.; Mørch-Reiersen, Lisa T. & Garstad, Kjersti W. [Vis alle 7 forfattere av denne artikkelen] (2016). Changes in lifestyle and risk factor levels after identification of and alerting to high cardiovascular risk: a randomized controlled trial of healthy subjects visiting Norwegian pharmacies.
• Narverud, Ingunn; van Lennep, Jeanine Roeters; Christensen, Jacob J.; Versmissen, Jorie; Gran, Jon Michael & Iversen, Per Ole [Vis alle 14 forfattere av denne artikkelen] (2016). What is the impact of maternal inheritance of FH on lipids and CRP in children with FH?
• Mehlum, Ingrid Sivesind; Corbett, Karina; Gran, Jon Michael & Kristensen, Petter (2015). Do psychosocial working conditions mediate social inequalities in musculoskeletal and psychiatric sickness absence in a life-course perspective?
• Mehlum, Ingrid Alethe Sivesind; Corbett, Karina; Gran, Jon Michael & Kristensen, Petter (2014). The relationship between socioeconomic position, working conditions and sickness absence in a life-course perspective.
• Narverud, Ingunn; van Lennep, Jeanine Roeters; Christensen, Jacob Juel; Versmissen, Jorie; Gran, Jon Michael & Iversen, Per Ole [Vis alle 15 forfattere av denne artikkelen] (2014). Cardiovascular risk markers in a large cohort of children and adolescents with genetically verified familial hypercholestelemia show no inheritance-related but LDL receptor mutation type- and family history of cardiovascular disease-related variance.
• Dalen, E; Sponheim, D; Torsvik, H; Lind, E; Dyrhaug, O & Gran, Jon Michael [Vis alle 7 forfattere av denne artikkelen] (2008). ASGE and EPAGE guidelines are an important help to select and prioritise patients referred to colonoscopy. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 43, s. 36–36.
• Gran, Jon Michael (2008). Estimating the causal effect of treatment on survival from HIV - A sequential Cox approach.
• Vorland, lars; Bovim, Gunnar; Gran, Jon Michael; Grødeland, Gunnveig; Hjort, Ingrid & Kristoffersen, Kathrine [Vis alle 11 forfattere av denne artikkelen] (2021). EKSPERTUTVALGET OM VIRUSVEKTORVAKSINER - Vurderinger av virusvektorvaksiner i og utenfor vaksinasjonsprogrammet. Regjeringen.no.
• Hoff, Rune & Gran, Jon Michael (2018). Causal inference in event history analysis with complex longitudinal data. Universitetet i Oslo Institutt for klinisk medisin; Universitetet i Oslo Det medisinske fakultet. ISSN 9788283772982.

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