Schedule, syllabus and examination date

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Course content

The course can be used as part of the curriculum for a MSc or PhD in toxicology or ecotoxicology. The course is offered in the autumn semester immediately following the course in general toxicology (BIO 4500). The course can form part of the theoretical basis for recognition as an EUROTOX-registered toxicologist.

Learning outcome

The course offers advanced subjects in mammalian toxicology, including toxicokinetics, chemical carcinogenesis, reproductive toxicology, occupational toxicology, neurotoxicology, developmental toxicology, respiratory toxicology, in vitro toxicology and epidemiology. Upon completing the course students should achieve an up-to-date knowledge of the most important areas of mammalian toxicology.


Students who are admitted to study programmes at UiO must each semester register which courses and exams they wish to sign up for in Studentweb.

If you are not already enrolled as a student at UiO, please see our information about admission requirements and procedures.

PhD-students must register for BIO9540.

The courses BIO4540 and BIO9540 have common admission. Applicants are ranked by the following criteria:
1. PhD students and master students at the MN faculty who have the course as part of the approved curriculum.
2. Other PhD students and visiting PhD students.
3. Students with admission to single courses on master’s level and exchange students
4. Applicants are ranked by credits in each group; all applicants within 1st rank before applicants in 2nd etc. If admission is limited to a fixed number of participants, admission will be decided by drawing lots for students who are ranked equally


Formal prerequisite knowledge

BIO4500 – General Toxicology (continued) (can be taken before BIO4540/4550, the same semester)

Recommended previous knowledge

Knowledge of chemistry, biochemistry and/or physiology.


The course will be given in week 40-45 each autumn semester. The course consists of lectures and discussion groups. Lectures will mainly be given by researchers from external institutions. All students will be expected to give a short presentation (15 min) over a subject provided.

First lecture is mandatory.  If you can not attend the first lecture, please send a note to, before the first lecture.

Access to teaching

A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.


Presentation (20%), and a three hours final written exam in week 45 (80%). All parts , exam and presentation must be passed to pass the course.

Examination support material

No examination support material is allowed.

Language of examination

You may submit your response in Norwegian, Swedish, Danish or English. If you would prefer to have the exam text in English, you may apply to the course administrators.

Grading scale

Grades are awarded on a scale from A to F, where A is the best grade and F is a fail. Read more about the grading system.

Explanations and appeals

Resit an examination

This course offers both postponed and resit of examination. Read more:

Special examination arrangements

Application form, deadline and requirements for special examination arrangements.


The course is subject to continuous evaluation. At regular intervals we also ask students to participate in a more comprehensive evaluation.


The subject requires more than three students to be given.

Facts about this course






Every autumn

The course is offered for the last time Autumn 2017. From 2018 it is replaced in parts by BIOS5411 and BIOS5412


Every autumn

Teaching language

Norwegian (English on request)