INF-BIO5120 – High Throughput Sequencing technologies and bioinformatics analysis

Schedule, syllabus and examination date

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Course content

The course provides knowledge of high throughput sequencing technologies and the analysis of data from various sequencing platforms and applications. Control of quantity and quality of data, analysis of small RNA-seq and mRNA-seq, de novo genome assembly, and variant calling. The course will also make use of the frameworks Galaxy and The Genomic Hyperbrowser in the analyses.

Learning outcome

  • The students will achieve a basic understanding of how to analyse different genomic data using different high throughput sequencing technologies.
  • You will be able to perform quantity- and quality control of sequencing data.
  • You can perform analysis of data from exome sequencing, micro RNA and mRNA sequences.
  • You can perform variant calling and identify SNPs and indels
  • You have knowledge about de novo assembly of genomes.
  • You are able to use the frameworks Galaxy and The Genomic Hyperbrowser.


Students who are admitted to study programmes at UiO must each semester register which courses and exams they wish to sign up for in Studentweb.

If you are not already enrolled as a student at UiO, please see our information about admission requirements and procedures.

A maximum of 15 students (INF-BIO5120 and INF-BIO9120 alltogether).

1) Phd students who have the course as mandatory
2) Master students at the Faculty of Mathematics and Natural Sciences who have the course approved in their study plan
3) Master students at the Faculty of Mathematics and Natural Sciences
4) Others


Recommended previous knowledge

We recommend that students with informatics background has INF4350 and students with a background from biology or molecular biology has MBV3070.


Two weeks of intensive teaching during the semester.

2/3 attendance is required.


Home exam.

Grading scale

Grades are awarded on a pass/fail scale. Read more about the grading system.

Explanations and appeals

Resit an examination

This course offers both postponed and resit of examination. Read more:

Withdrawal from an examination

It is possible to take the exam up to 3 times. If you withdraw from the exam after the deadline or during the exam, this will be counted as an examination attempt.

Special examination arrangements

Application form, deadline and requirements for special examination arrangements.

Facts about this course






Every autumn


Every autumn

Teaching language