MEDFL5195 – OMICs in medical research

Schedule, syllabus and examination date

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Course content

The purpose of the course is to introduce the use of various Omics technologies, which aim to collectively characterize pools of biological molecules in a single experiment. The focus is Omics technologies in medical research today and tomorrow. The understanding of strengths and limitation of Omics technologies is fundamental for the selection of appropriate analyses and for the interpretation of results obtained.

The course will be based on selected clinical problems and present different experimental strategies, including a description on the principles behind the methods. The strengths and weaknesses of each technology will be discussed with a focus on the decisions that guide the choice of an experimental strategy. Hands on sessions in computational data analyses are included in order to train in performing experiments in given technologies.

The candidate will learn about selected Omics technologies and their strengths and limitations. The candidate will also learn underlying principles of these technologies and how to critically judge the robustness of the Omics data.

Learning outcome

This course will give you knowledge about:

  • Overview of genome variation in the population including technologies to detect these
  • Understanding how High-throughput DNA sequencing (HTS) can be used to identify disease causing genetic variants in monogenic diseases
  • Understanding how GWAS can detect disease associated markers in multifactorial diseases
  • Understanding how HTS technologies can be used to explore changes in gene expression
  • Understanding how mass-spectrometry (MS) analyses can be used in quantitative and qualitative proteomics experiments
  • Understanding how Nuclear magnetic resonance (NMR) analyses can be used in metabolomics experiments
  • Understanding principles behind basic data analysis tasks in Omics, and the integration of Omics data
  • Application of various Omics technologies
  • Critical selection of Methods
  • Understanding how metagenomics can be used to explore the gut microbiome
  • Understanding principles behind high content imaging
  • Understanding principles behind brain connectomics


The course is restricted to students at the Medical Student Research Programme at the Faculty of Medicine and the Faculty of Dentistry, UiO.

MEDFL5195 has common admission with MF9195.

Course registration:

  • Students apply in StudentWeb.
  • Enrollment to this course is automatically registered in StudentWeb
  • Applicants will upon registration immediately receive a reply in StudentWeb if the application is granted.

Overlapping courses

5 credits overlap with MF9195 – OMICs in medical research


The course will run for 5 full days and mainly based on lectures supplemented with hands on training on computers.

Teaching is mainly by lectures. There will also be group work with hands on training in a PC room focusing on analysis of genomics and proteomics data.

You have to participate in at least 80 % of the teaching to be allowed to take the exam. Attendance will be registered.


The written home exam will have to be submitted two weeks after the course.

The exam paper is in English. It is optional for the candidate to answer the exam in Norwegian or English

Submit assignments in Inspera

You submit your assignment in the digital examination system Inspera. Read about how to submit your assignment.

Use of sources and citation

You should familiarize yourself with the rules that apply to the use of sources and citations. If you violate the rules, you may be suspected of cheating/attempted cheating.

Grading scale

Grades are awarded on a pass/fail scale. Read more about the grading system.

Explanations and appeals

Resit an examination

Withdrawal from an examination

It is possible to take the exam up to 3 times. If you withdraw from the exam after the deadline or during the exam, this will be counted as an examination attempt.

Special examination arrangements

Application form, deadline and requirements for special examination arrangements.


The course is subject to continuous evaluation. At regular intervals we also ask students to participate in a more comprehensive evaluation.

Facts about this course






Every spring

Teaching spring 2022: 2.5.- 6.5. Application period: 1.12.2021 - 1.4.2022.

Course registration:  Students apply in StudentWeb.


Every spring

Teaching language