MEDFL5495P – Course In Animal Research In Norway (CAREiN) - Practical training in handling of laboratory rodents

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Course content

Practical training in handling of laboratory rodents is an integral part of the course MEDFL5495T  (or a similar theoretical experimental animal course (e.g. at UiT, NTNU, NMBU or UiB)) for all students that intend to perform and conduct hands-on animal experiments themselves (Function A and D). Practical training is also an integral part of the requirements in the Norwegian Regulation on Animal Experiment, § 24 and Annex E, Points 1-11, and adheres to the practical training requirements for Core Modules for function A and D in the EU Education and Training Framework. (Function A = person carrying out procedures on animals and D = killing of animals). The course qualifies for hands-on use of animals in research for persons with function A and D, in accordance with Articles 23 and 24 of the EU Directive 2010/63/EU.

MEDFL5495P is only a relevant course for students that have signed up for or previously completed MEDFL5495T, or a similar theoretical experimental animal course (e.g. at UiT, NTNU, NMBU or UiB). Such theoretical training must be completed and the course certificate approved to qualify for practical training with laboratory rodents prior to attending practical training.

Students that require practical training in handling of laboratory rodents are expected to complete such training in the lab animal facility at their own institution. The lab animal facility providing the training must adhere to the manual of practical training defined by the CAREiN consortium (UiT, NTNU, UiB and UiO). CAREiN accredited instructors at the animal facilities must organize the training.

See also MEDFL5495T Course In Animal Research In Norway (CAREiN) - Theoretical training

Learning outcome

The course provides introduction to and hand-on training of correct handling and basic experimental techniques used in rodents, according to the requirements in the EU Commissions Education and Training Framework Document. At the end of the practical training, the competence of the students will be assessed by their ability to accomplish defined assignments, enabling approved students to practice further under supervision of experienced personnel in their research team and/or department.

Admission

The course is restricted to students at the Medical Student Research Programme at the Faculty of Medicine and the Faculty of Dentistry, UiO.

  • Students register in StudentWeb.

  • After registration in StudentWeb you will receive a webform that you will be asked to fill out this in order to complete your registration to this course.

  • Answer to the course applicants will be sent by email continuously.

The courses MEDFL5495P and MF9495P have common admission.

Prerequisites

Formal prerequisite knowledge

Students that require admission to this course must have signed up for MEDFL5495T this semester, or previously completed MF9495T or a similar theoretical experimental animal course (e.g. at UiT, NTNU or UiB) with formal prerequisite knowledge as MEDFL5495T. Such theoretical training must be evaluated and approved by the course organizers prior to attending practical training (documentation of theoretical training must be submitted in the web form as described above).

Overlapping courses

2 credits overlap with Course in Laboratory Animal Science for Researchers, NMBU

Teaching

The teaching will consist of:

Three days of mandatory practical training in handling of laboratory rodents (mice and rats).

Practical training in handling of laboratory rodents (mice and rats) must be provided by CAREiN accredited instructors. CAREiN institutions with accredited CAREiN instructors includes UiO, UiT, NTNU, NMBU and UiB. Students shall attend practical training organized by the animal facility in the CAREiN institution where the student belongs to/will be working in after completion of the course. Practical training will be assigned to the nearest CAREiN-facility if own institution is not a CAREiN-facility. The lab animal facility providing the practical training must adhere to the manual of practical training in rodents, as defined by the CAREiN consortium (UiO, UiT, NTNU, UiB and NMBU).

Time slots for practical training:

The majority of course participants attend MEDFL5495T and MEDFL5495P in the same semester. Time slots for practical training will vary between animal research facilities and will be scheduled after completion of the obligatory test in MEDFL5495T the same semester. Time slots for each training facility will be announced via Canvas for this course (MEDFL5495P). Students at UiO will have the ability to sign themselves up to the preferred time-slot at their own institution. Students outside UiO will be informed of rules for practical training at their own institution via Canvas.

Practical training in pigs or model fish:

Students planning to use other species covered in the theoretical modules of CAREiN (pigs or model fish) must organize an additional minimum 14 hours of relevant training with these species according to learning objectives defined by the course committee. Supervisor(s) providing such training in practical handling and use of pigs or model fish must certify such training and the certificate must be provided for approval to the course committee.

Participation in practical training with rodents (MEDFL5495P) is a prerequisite for obtaining a passed course certificate in other species included in the theoretical training.

 

Teaching in basic techniques in rodents:

Students participating in the practical training of CAREiN will be introduced to animal handling and the most basic techniques with rodents. The students must practice these under competent supervision. The goal of the course is for the students to achieve basic skills, thus enabling them to practice further under the supervision of their own research team/ department.

Practical training in basic techniques - mice:

  • Observation and characterization of normal mice behavior.
  • Euthanasia by CO2 and cervical dislocation.
  • Physical handling (lifting and transporting mice), restraint, and earmarking.
  • Injections (IP, SC) and blood sampling (vena saphena, pedal vein).
  • Dissection and harvest of organs.

Practical training in basic techniques - rat:

  • Observation and characterization of normal rat behavior.
  • Physical handling (lifting and moving rats), restraint.
  • Injections (IP, SC) and blood sampling (vena saphena, pedal vein).

Additional optional techniques may be teached, based on student competence and needs.

To pass the course, students must demonstrate their ability to perform the listed practical skills according to defined competence criteria.

Examination

To pass the practical training and be allowed to practice further under the supervision of experienced personnel and eventually perform and conduct animal experiments on their own, the student must demonstrate sufficient competence during practical handling and performance of procedures with experimental animals.

 

Course Diploma

In order to complete the MEDFL5495P course and get a course certificate for the EU Functions A+B+D, the student must document theoretical training in mice and rodents (MEDFL5495T or equal course) and pass organized practical training in rodents provided in MEDFL5495P.

Provided that MEDFL5495T and MEDFL5495P has been passed, a Functions A+B+D certificate will be issued to students that demonstrate required theoretical training and basic practical skills in rodents. The course diploma will be issued by the Student administration.

Course certificate in other species:

Participation in practical training with rodents (MEDFL5495P) is a prerequisite for obtaining a passed course certificate in other species included in the theoretical training.

Evaluation

The course is subject to continuous evaluation. At regular intervals we also ask students to participate in a more comprehensive evaluation.

Facts about this course

Credits

2

Level

Master

Teaching

Spring and autumn

Teaching spring 2022: Period for practical training: To be announced.

 Lecture: Obligatory introductory lecture January 26, 12.00-13.00. This lecture will be given in Zoom.

 Application period: 1.12.2021 - 5.1.2022.

Course registration:  See information on how to apply in the section "Admission" in the course description below.

Inquries about registration and course certificate should be sent to adm-phd-emner@medisin.uio.no

Note that due to Covid19 changes may occur.

Examination

Spring and autumn

Teaching language

English