BIOS5912 – Eukaryotic Transcription Factors - Structures, Function, Regulation

Schedule, syllabus and examination date

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Changes in the course due to coronavirus

Spring 2021 the exams of most courses at the MN Faculty will be conducted as digital home exams or oral exams, using the normal grading scale.

As a general rule, exams at the MN Faculty will during the autumn of 2021 be conducted without physical attendance. For reasons relating to the course content, some courses will have on-campus written examination if the current infection rate makes this possible.

The semester page for your course will be updated with any changes in the form of examination. See also more information about examination at the MN Faculty in 2021.

Course content

The course focuses on current understanding of the structure and function of eukaryotic transcription factors. The aim of the first general part is to give the student an understanding of the main components of the eukaryotic transcription apparatus. Topics covered are: promoters, RNA polymerase II, general transcription factors and coactivators, the role of chromatin structure in transcription, elongation control and the mechanisms of gene activation, as well as nuclear organization. In the second part, specific transcription factors are discussed: homeodomain and POU families, bZIP- and HLH-families, zinc-finger families, the NFkB-family, nuclear receptors, the FOX- and Myb-family, STAT family, p53 and Rb to illustrate the connection between oncogenesis and transcription.

Learning outcome

After completing the course you are expected to have knowlegde about and an overview of the research front in subjects such as:

  • understand central aspects of the complex structure and function of the transcription apparatus which regulates the expression of genes in eucaryotic cells.  
  • understand resent research the field of eukaryotic transcription.

Admission to the course

Students admitted at UiO must apply for courses in Studentweb. Students enrolled in other Master's Degree Programmes can, on application, be admitted to the course if this is cleared by their own study programme.

Nordic citizens and applicants residing in the Nordic countries may apply to take this course as a single course student.

If you are not already enrolled as a student at UiO, please see our information about admission requirements and procedures for international applicants.

BIOS3900 – Biochemistry 2, BIOS4010 – Methods in Molecular Biology and Biochemistry I, BIOS4020 – Methods in Molecular Biology and Biochemistry II  or corresponding knowledge.

Overlapping courses

Teaching

  • Lectures
  • Seminars with a 15 minutes presentations of a scientific article for the other students

Attendance is mandatory for the first lecture. This also applies to those on the waiting list. You will lose your seat on the course if documentation for absence is not provided to the student administration studieinfo@ibv.uio.no prior to the first lecture.

Examination

  • Final written exam, which counts 100 % towards the finale grade. 

This course has mandatory assignments that must be approved before you can sit the finale exam.

Optional oral exam depending on the number of participants.

It will also be counted as one of the three attempts to sit the exam for this course, if you sit the exam for one of the following courses: MBV4230 – Eukaryotic Transcription Factors - Structures, Function, Regulation (continued), MBV9230 – Eukaryotic Transcription Factors - Structures, Function, Regulation (continued), BIOS9912 – Eukaryotic Transcription Factors - Structures, Function, Regulation

Examination support material

No examination support material is allowed.

Language of examination

Subjects taught in English will only offer the exam paper in English. You may write your examination paper in Norwegian, Swedish, Danish or English.

Grading scale

Grades are awarded on a scale from A to F, where A is the best grade and F is a fail. Read more about the grading system.

Resit an examination

This course offers both postponed and resit of examination. Read more:

Special examination arrangements, use of sources, explanations and appeals

See more about examinations at UiO

Last updated from FS (Common Student System) Aug. 2, 2021 12:17:18 PM

Facts about this course

Credits
10
Level
Master
Teaching
Autumn
Examination
Autumn
Teaching language
English