KJM5240 – Mass Spectrometry
Schedule, syllabus and examination date
Teaching and exams spring 2022
In light of the most recent infection control regulations, we will at the start of the spring semester 2022 increase our online teaching, while we at the same time try to maintain in-person teaching where this is possible. We hope to go back to more in-person teaching later on in the semester. You will be informed about any changes in teaching or examinations on the semester page, in Canvas or through your regular channels.
Read more about postponed exams for the autumn semester 2021.
This course is addressed to unexperienced mass spectrometry users from various fields (e.g., chemistry, biology, pharmacy, medicine, physics, geology) who want to understand how their instrument works and how to properly interpret the obtained data. Although no hands-on is provided, the course is very much oriented towards helping you with your everyday work on a mass spectrometer, equipping you with the essential technical and chemical-analytical knowledge.
After completing this course, you:
- understand how the most common mass analyzers work: quadrupole (QMS), triple quadrupole (TQMS), cylindrical and linear ion trap (CIT-MS, LIT-MS), Fourier transform ion cyclotron resonance (FT-ICR-MS), Orbitrap-MS, time-of-flight (TOF-MS), and magnetic sector MS analyzers.
- know the principles of the main ionization methods that are currently in use: electron ionization (EI), chemical ionization (CI), Penning ionization (PeI), electron capture negative ionization (ECNI), photoionization (PI), matrix-assisted laser desorption ionization (MALDI), fast atom bombardment (FAB), and electrospray ionization (ESI).
- understand the ion chemical and physical processes in an ion source and be able to choose the best ionization method for your sample
- are able to understand and describe the chemical-analytical performance of a mass spectrometer (mass resolution, mass accuracy, sensitivity, limit of detection, etc.)
- are able to interpret mass spectra (mostly ESI-generated) and know the basic principles of ion fragmentation.
Admission to the course
Students admitted at UiO must apply for courses in Studentweb. Students enrolled in other Master's Degree Programmes can, on application, be admitted to the course if this is cleared by their own study programme.
Nordic citizens and applicants residing in the Nordic countries may apply to take this course as a single course student.
If you are not already enrolled as a student at UiO, please see our information about admission requirements and procedures for international applicants.
- 10 credits overlap with KJM9240 – Mass Spectrometry.
The course duration is one semester, and consists of:
- 30 hours of lectures
- 15 hours of exercises.
- Final oral exam which counts 100% towards the final grade.
It will also be counted as one of the three attempts to sit the exam for this course, if you sit the exam for one of the following courses: KJM9240 – Mass Spectrometry
Examination support material
Smartphone or notebook (for using online MS interpretation tools)
Grades are awarded on a scale from A to F, where A is the best grade and F is a fail. Read more about the grading system.
Resit an examination
This course offers both postponed and resit of examination. Read more: