FARM2100 – Medicinal chemistry
The subject deals with the chemistry of the drug substances and how the chemical properties of the drug substances affect the biological profile of the drugs. The course deals with topics such as synthesis, stability and structural activity for the most important drug groups.
After completing the course:
- you will have broad knowledge of general principles in medicinal chemistry and specific knowledge of the medicinal chemistry related to the most important drug groups.
- you will have broad knowledge of the preparation (including synthesis), chemical properties, stability, metabolism and structural activity (SAR) of drug substances.
- you should, based on the chemical structure of a drug substance, be able to apply principles in drug chemistry and understand possible biological properties in relation to interaction with target molecules, route of administration, formulation, biodistribution, metabolism and excretion.
- you should, based on the basis of interdisciplinary drug-related texts such as “Felleskatalog”-text, be able to explain the topics that are directly chemically related and should also be able to actively participate in discussion of other drug-related topics where these may be related to the structure and chemical properties of the drug substances.
- you can evaluate and convey results from laboratory exercises in a scientific report.
The course is only available to students enrolled at the Department of Pharmacy at the University of Oslo.
Formal prerequisite knowledge
- The compulsory parts of FARM1100 – Pharmaceutical Chemistry and FARM1130 – Pharmaceutical Based Organic Chemistry
- The compulsory HSE-courses HMS0501 – Safety and Physical Environment, HMS0502 – Positive Learning Environment, HMS0503 – Laboratory Safety, HMS0506 – Patient Clinic Safety and HMS0507 – Fire Safety required for students at the 5-year Master`s Program in Pharmacy
Recommended previous knowledge
- 5 credits overlap with FRM2000 – Drugs and How They Work Part II
- 5 credits overlap with FARM2105 – OE i legemiddelkjemi
The information about overlaps is not complete.
- Approx. 30 hours of lectures
- Approx. 20 hours of colloquia
- Approx. 20 hours laboratory course (mandatory)
Compulsory participation in the course must be completed and approved and compulsory submissions must be approved to pass the exam.
As the teaching involves laboratory and/or field work, you should consider taking out a separate travel and personal risk insurance. Read about your insurance cover as a student.
Access to teaching
A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.
Completed and approved compulsory instruction and coursework are valid for 3 years.
Written digital exam 4 hours
For admission to the exam, the approved laboratory course is required.
The written examination is conducted in the digital examination system Inspera. You will need to familiarize yourself with the digital examination arrangements in Inspera.
Examination support material
As of 1 August, 2016, the use of own calculators is no longer permitted. Casio FX-991EX calculators are handed out to all exam candidates at the beginning of the exam.
Language of examination
You may write your examination paper in Norwegian, Swedish or Danish.
Grades are awarded on a scale from A to F, where A is the best grade and F is a fail. Read more about the grading system.
Explanations and appeals
Resit an examination
This course offers both postponed and resit of examination. Read more:
Withdrawal from an examination
It is possible to take the exam up to 3 times. If you withdraw from the exam after the deadline or during the exam, this will be counted as an examination attempt.
Special examination arrangements
Application form, deadline and requirements for special examination arrangements.
The course is subject to continuous evaluation. At regular intervals we also ask students to participate in a more comprehensive evaluation.