FARM2100 – Medicinal Chemistry

After completing the course:

• you will have broad knowledge of general principles in medicinal chemistry and specific knowledge of the medicinal chemistry related to the most important drug groups.
• you will have broad knowledge of the preparation (including synthesis), chemical properties, stability, metabolism and structural activity (SAR) of drug substances.
• you should, based on the chemical structure of a drug substance, be able to apply principles in drug chemistry and understand possible biological properties in relation to interaction with target molecules, route of administration, formulation, biodistribution, metabolism and excretion (ADME).
• you should, based on the basis of interdisciplinary drug-related texts such as "Felleskatalog"-text, be able to explain the topics that are directly chemically related and should also be able to actively participate in discussion of other drug-related topics where these may be related to the structure and chemical properties of the drug substances.
• you can practically apply central laboratory methods for the synthesis and evaluation of drug compounds with the aim of developing structure-activity relationships.
• you can evaluate and convey results from laboratory exercises in a scientific report.

The course is only available to students enrolled at the Department of Pharmacy at the University of Oslo.

Pregnant and breastfeeding: For safety reasons, pregnant and breastfeeding women cannot participate in laboratory exercises in this course. This is due to the use of chemicals in the laboratory exercises that may be harmful to the fetus or child. No exemptions or accommodations for the laboratory exercises will be granted, as these must be completed and approved to fulfill the learning outcomes of the course. Students affected by this should contact the Study administration at the Department of Pharmacy for more information.

• FARM1100 – Pharmaceutical Chemistry
• FARM1110 – Pharmacology, Physiology and Cell Biology 1
• FARM1120 – Social Pharmacy
• FARM1130 – Pharmaceutically Based Organic Chemistry
• FARM1140 – Pharmacology, Physiology and Cell Biology 2
• FARM1150 – Pharmaceutical Based Biochemistry
• The compulsory HSE-courses HMS0501 – Safety and Physical Environment, HMS0502 – Positive Learning Environment, HMS0503 – Laboratory Safety, HMS0506 – Patient Clinic Safety and HMS0507 – Fire Safety required for students at the 5-year Master`s Programme in Pharmacy.

Course exemption: Laws and regulations describing the overall learning outcome regulate the Pharmacy programme. Exemptions are only granted if all learning outcomes in the course are covered.

The information about overlaps is not complete.

• 30 hours of lectures - the introductory lecture is compulsory
• 22 hours of colloquia
• 20 hours laboratory course (compulsory)
• active participation in preparing and presenting a mini-lecture together with other students (compulsory)

Compulsory participation in the course must be completed and approved and compulsory submissions must be approved to sit the exam. Read more about what applies in the event of absence from compulsory activities (only in Norwegian).

As the teaching involves laboratory and/or field work, you should consider taking out a separate travel and personal risk insurance. Read about your insurance cover as a student.

Access to teaching: A student who has completed compulsory instruction and coursework and has had these approved, is not entitled to repeat that instruction and coursework. A student who has been admitted to a course, but who has not completed compulsory instruction and coursework or had these approved, is entitled to repeat that instruction and coursework, depending on available capacity.

Completed and approved compulsory instruction and coursework are valid for 3 years.

Final written exam, which counts 100 % towards the final grade.

This course has compulsory exercises that must be approved before you can sit the final exam.

The periodic table of the elements.

Casio FX-991EX calculators are handed out to all exam candidates at the beginning of the exam.

This course offers both postponed and resit of examination. Read more:

• Illness at exams / postponed exams
• Withdrawal during an examination / Resitting an examination