KJM5280 – NMR Spectroscopy

After completion of the course, you:

• can calibrate an NMR spectrometer (lock, tune/match, shim) to a new sample
• are able to prepare and execute manual NMR experiments with the nuclei 1H, 13C, 19F, and 31P across old and new spectrometers.
• can use the semi automation program IconNMR as a helping tool for running a series of 2-dimensional NMR-experiments (COSY, TOCSY, NOESY, ROESY, HSQC, HMBC, SHSQC, SHMBC and simultaneous 1H-19F experiments) and are also able to perform simple solvent suppression experiments
• can process and understand the information content in two-dimensional NMR experiments
• can apply the results coming out of NMR experiments in research where the goal is to identify an unknown molecule

Students admitted at UiO must apply for courses in Studentweb. Students enrolled in other Master's Degree Programmes can, on application, be admitted to the course if this is cleared by their own study programme.

Nordic citizens and applicants residing in the Nordic countries may apply to take this course as a single course student.

If you are not already enrolled as a student at UiO, please see our information about admission requirements and procedures for international applicants.

Due to the registration of user IDs on instrument PCs, intensive teaching, and mandatory use of instruments, it is not possible to register for this course less than one week before the teaching starts.

Before you can attend the mandatory laboratory courses, you have to have passed the following courses:

• HMS0503 – Laboratory Safety
• HMS0507 – Fire Safety

• KJM3000 – Applied Spectroscopy and KJM3200 – Organic Chemistry II

The course extends over the whole semester. The teaching consists of the following:

• Practical and intensive training in NMR spectroscopy on NMR spectrometers in approximately 4 full days. The training can take place in pairs or individually as desired. The student then records additional data on his/her own without guidance.
• 3 lectures of 2 hours each on basic NMR theory, instrument calibration, overview of 2D techniques, parameter settings, and report writing. The last lecture also provides an insight into more advanced NMR experiments.
• Practical exam on an NMR spectrometer of 1 hour, typically 1-3 weeks after completing practical training. The exam must be passed before submitting a written report and conducting an oral presentation.

As the teaching involves laboratory and/or field work, you should consider taking out a separate travel and personal risk insurance. Read about your insurance cover as a student.

The course does not have a classical exam. Two following evaluations has to be passed for getting the course approved:

• One hour practical test at a NMR spectrometer.
• Submission of a written report on the identification of an unknown molecule.

The practical test needs to be passed before you can hand in the written report.

It will also be counted as one of the three attempts to get this course approved if you go through the same approval procedure for one of the following courses: KJM9280 – NMR Spectroscopy